<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2016-03-10</periodOfReport>

    <issuer>
        <issuerCik>0000008328</issuerCik>
        <issuerName>Applied Minerals, Inc.</issuerName>
        <issuerTradingSymbol>AMNL</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001531775</rptOwnerCik>
            <rptOwnerName>GLEESON WILLIAM</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>110 GREENE STREET</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 1101</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10012</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>General Counsel</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>COMMON STOCK OPTION (RIGHT TO BUY)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.24</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2016-03-10</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>248344</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.24</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2016-03-10</value>
            </exerciseDate>
            <expirationDate>
                <value>2021-03-10</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>COMMON STOCK</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>248344</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1820750</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">On March 10, 2016, Mr. Gleeson was granted an option to purchase 248,344 shares of common stock of Applied Minerals, Inc. at $0.24 per share.  The exercise price is the closing price of the Company's common stock on March 9, 2016. The option vests immediately and expires on March 10, 2021. This grant was a component of Mr. Gleeson's bonus for work performed during 2015 as determined by the Company's Board of Directors.  The Black-Scholes value of the option grant is $37,500.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Wiliam Gleeson</signatureName>
        <signatureDate>2016-03-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
