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Note 6 - Stock-based Compensation (Tables)
12 Months Ended
Dec. 31, 2025
Notes Tables  
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
   

2025

   

2024

 

Weighted average risk-free interest rates

    4.5 %     3.8 %

Expected dividend yield

    0.0 %     0.0 %

Expected life of option (in years)

    7.0       7.0  

Expected volatility

    179.3 %     204.2 %
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
   

2025

   

2024

 

Stock options:

               

Research and development

  $ 513,867     $ 222,202  

General and administrative

    597,120       252,275  

Total stock option expense

    1,110,987       474,477  

Stock awards:

               

General and administrative

    4,167       54,167  

Total stock-based compensation expense

  $ 1,115,154     $ 528,644