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Note 3 - Balance Sheet Components (Tables)
12 Months Ended
Dec. 31, 2025
Notes Tables  
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
   

2025

   

2024

 

Prepaid clinical trial costs

  $ 1,197,679     $ 1,524,813  

Prepaid insurance premiums

    165,067       220,675  

Prepaid rent

    16,000       13,045  

Prepaid contract manufacturing costs

    783,321       -  

Other

    66,843       10,000  

Total prepaid expenses

  $ 2,228,910     $ 1,768,533  
Property, Plant and Equipment [Table Text Block]
   

2025

   

2024

 

Equipment and furnishings

  $ 512,437     $ 795,411  

Leasehold improvements

    -       115,605  

Total property and equipment

    512,437       911,016  

Accumulated depreciation and amortization

    (403,607 )     (761,042 )

Total property and equipment, net

  $ 108,830     $ 149,974  
Schedule of Other Assets [Table Text Block]
   

2025

   

2024

 

Prepaid technology license fees

  $ 50,000     $ 60,000  

Deposits

    36,947       11,010  

Total other assets

  $ 86,947     $ 71,010  
Schedule of Accrued Liabilities [Table Text Block]
   

2025

   

2024

 

Payroll-related liabilities

  $ 181,584     $ 986,691  

Accrued clinical trial costs

    587,303       200,881  

Other accrued expenses

    113,929       70,000  

Total accrued expenses

  $ 882,816     $ 1,257,572