Note 9 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2024

Notes Tables

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

	2024			2023
Deferred tax assets:
Net operating loss carryforward	$	30,374,640		$	25,527,210
Research and development tax credit carryforward		5,506,154			3,870,460
Stock-based compensation expense		676,250			552,886
Accrued expenses		256,540			29,728
Total deferred tax assets		36,813,584			29,980,284
Deferred tax liabilities
Depreciation		29,812			45,122
Net deferred tax assets		36,783,772			29,935,162
Valuation allowance		(36,783,772	)		(29,935,162	)
Net deferred tax asset after reduction for valuation allowance	$	-0-		$	-0-

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

	2024			2023
U.S. federal statutory rate applied to pretax loss		21.0	%		21.0	%
State income tax (benefit)		4.0			3.9
Permanent differences		(0.0	)		(0.0	)
NOL carryforward expiration		(4.1	)		(4.3	)
R&D tax credits, net of expiration		6.5			6.4
Change in valuation allowance and other adjustments		(27.4	)		(27.0	)
Effective tax rate		0.0	%		0.0	%