Note 7 - Stock-based Compensation Expense (Tables)

12 Months Ended

Dec. 31, 2024

Notes Tables

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

Weighted average risk-free interest rates	3.8	%
Expected dividend yield	0.0	%
Expected life of option (in years)	7.0
Expected volatility	204.2	%

Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]

	2024		2023
Stock options:
Research and development	$	222,202	$	291,094
General and administrative		252,275		564,030
Total stock option expense		474,477		855,124
Stock awards:
General and administrative		54,167		219,833
Total stock-based compensation expense	$	528,644	$	1,074,957