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Note 8 - Stockholders' Equity (Details Textual) - USD ($)
3 Months Ended 12 Months Ended
Jan. 19, 2022
Feb. 11, 2021
Sep. 29, 2020
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Sep. 30, 2021
Stock Issued During Period, Value, New Issues   $ 10,300,000     $ 9,408,920 $ 9,408,920 $ 11,158,496  
Proceeds from Issuance or Sale of Equity, Total     $ 11,200,000          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)           360,300    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number, Ending Balance (in shares)           962,300 602,000  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance (in dollars per share)           $ 3.18 $ 2.79  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term (Year)           9 years 3 months 21 days    
Class of Warrant or Right, Outstanding (in shares)           2,816,631    
Stock Incentive Plan 2020 [Member]                
Common Stock, Capital Shares Reserved for Future Issuance (in shares)       1,500,000       1,500,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares)       0        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number, Ending Balance (in shares)       962,300        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance (in dollars per share)       $ 3.18        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term (Year)       9 years 1 month 6 days        
Pre-Funded Warrants [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) 2,360,000              
Common Warrant [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) 3,067,484              
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) $ 3.26              
Stock Purchase Warrants [Member]                
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)       $ 4.23        
Class of Warrant or Right, Outstanding (in shares)       5,884,115        
Warrants and Rights Outstanding, Term (Year)       4 years 2 months 12 days        
Private Placement [Member]                
Stock Issued During Period, Value, New Issues $ 707,484              
Proceeds from Issuance or Sale of Equity, Total $ 9,200,000