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Note 5 - Property and Equipment - Schedule of Property and Equipment (Details) - USD ($)
Mar. 31, 2020
Dec. 31, 2019
Property and equipment, gross $ 661,918 $ 661,918
Accumulated depreciation and amortization (652,306) (651,312)
Property and equipment, net 9,612 10,606
Laboratory Equipment [Member]    
Property and equipment, gross 534,577 534,577
Leasehold Improvements [Member]    
Property and equipment, gross 115,605 115,605
Other Furniture Fixtures And Equipment [Member]    
Property and equipment, gross $ 11,736 $ 11,736