Note 8 - Common Stock (Details Textual) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Stock Issued During Period, Shares, Issued for Services	17,500,000
Common Stock, Capital Shares Reserved for Future Issuance	265,565,942
2006 Equity Incentive Plan [Member]
Common Stock, Capital Shares Reserved for Future Issuance	1,412,300
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period	10 years
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period	3 years
2006 Equity Incentive Plan [Member] | Incentive Stock Options (ISO's) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent	110.00%
Equity Incentive Plan 2016 [Member]
Common Stock, Capital Shares Reserved for Future Issuance	16,000,000
Expense Associated with Warrant Modifications [Member]
Stock Issued During Period, Shares, Warrants Exercised		31,639,577	21,884,420
Proceeds from Warrant Exercises		$ 571,511	$ 1,339,801
Conversion from Series C and Series D Convertible Preferred Stock to Common Stock [Member]
Conversion of Stock, Shares Issued	94,666,666	19,862,000	1,400,000