X0306 4 2020-03-12 0 0000831547 SPECTRUM PHARMACEUTICALS INC SPPI 0001462354 GUSTAFSON KURT A 11500 S. EASTERN AVE. SUITE 240 HENDERSON NV 89052 0 1 0 0 EVP & Chief Financial Officer Common Stock, $0.001 2020-03-12 4 A 0 163180 0.00 A 368291 D Common Stock, $0.001 11840 I By 401(k) Plan Stock Option (Right to Buy) 2.13 2020-03-12 4 A 0 260000 0.00 A 2030-03-12 Common Stock 260000 260000 D Stock Appreciation Right 2.13 2020-03-12 4 A 0 225000 0.00 A 2030-03-12 Common Stock 225000 225000 D One third of the aggregate amount of restricted shares shall vest on each of March 12, 2021, 2022 and 2023, respectively. 25% of the option shares vested on March 12, 2020. The remaining option shares shall vest in equal amounts of 25% of the total shares underlying the option shares on each anniversary of the grant date over the next three years. 25% of the stock appreciation rights vested on March 12, 2020. The remaining stock appreciation rights shall vest in equal amounts of 25% of the total shares underlying the stock appreciation rights on each anniversary of the grant date over the next three years. The stock appreciation rights can be settled in common stock or cash at the election of the Compensation Committee. /s/ Kurt A. Gustafson 2020-03-13