X0306 4 2015-03-18 0 0000831547 SPECTRUM PHARMACEUTICALS INC SPPI 0001408474 ALLEN LEE F MD PhD 11500 S. EASTERN AVENUE SUITE 240 HENDERSON NV 89052 0 1 0 0 Chief Medical Officer Common Stock, $0.001 par value 2015-03-18 4 F 0 3049 6.38 D 83227 D Common Stock, $0.001 par value 3157 I by 401(K) Plan Represents restricted shares withheld by Spectrum to satisfy the Reporting Person's tax withholding obligations. The shares have not been sold by the Reporting Person or by Spectrum. The shares have been cancelled by the transfer agent and returned to Spectrum's authorized and unissued share pool. /s/ by Kurt A. Gustafson, attorney-in-fact for Lee F. Allen 2015-03-20