-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 FMcrtb/GWTfzl8G+bafOqkp6Qn6V4b99UKouDRBd82bRXRdjoyEyesEfOh72kb5k
 WwUGurRZUtQJgaT/Uw/I8A==

<SEC-DOCUMENT>0001209191-10-021723.txt : 20100409
<SEC-HEADER>0001209191-10-021723.hdr.sgml : 20100409
<ACCEPTANCE-DATETIME>20100409131021
ACCESSION NUMBER:		0001209191-10-021723
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100409
FILED AS OF DATE:		20100409
DATE AS OF CHANGE:		20100409

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SHROTRIYA RAJESH C MD
		CENTRAL INDEX KEY:			0001193918

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-28782
		FILM NUMBER:		10741935

	MAIL ADDRESS:	
		STREET 1:		157 TECHNOLOGY DRIVE
		CITY:			IRVINE
		STATE:			CA
		ZIP:			92618

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SPECTRUM PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000831547
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				930979187
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		157 TECHNOLOGY DR
		CITY:			IRVINE
		STATE:			CA
		ZIP:			92618
		BUSINESS PHONE:		9497886700

	MAIL ADDRESS:	
		STREET 1:		157 TECHNOLOGY DR
		CITY:			IRVINE
		STATE:			CA
		ZIP:			92618

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NEOTHERAPEUTICS INC
		DATE OF NAME CHANGE:	19960819

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AMERICUS FUNDING CORP
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-04-09</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000831547</issuerCik>
        <issuerName>SPECTRUM PHARMACEUTICALS INC</issuerName>
        <issuerTradingSymbol>SPPI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001193918</rptOwnerCik>
            <rptOwnerName>SHROTRIYA RAJESH C MD</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>701 N GREEN VALLEY PARKWAY</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 265</rptOwnerStreet2>
            <rptOwnerCity>HENDERSON</rptOwnerCity>
            <rptOwnerState>NV</rptOwnerState>
            <rptOwnerZipCode>89074</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chairman, CEO &amp; President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock $.001 Par Value</value>
            </securityTitle>
            <transactionDate>
                <value>2010-04-09</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>4.4355</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1153486</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes></footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/S/ Rajesh C. Shrotriya</signatureName>
        <signatureDate>2010-04-09</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----