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Mundipharma Agreements - Additional Information (Detail) (USD $)
6 Months Ended 1 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended
Sep. 05, 2012
Jun. 30, 2013
Maximum [Member]
Regulatory [Member]
Jun. 30, 2013
Maximum [Member]
Commercial progress- and sales-dependent [Member]
May 29, 2013
Mundipharma [Member]
Jun. 30, 2013
Mundipharma [Member]
Jun. 30, 2013
Mundipharma [Member]
May 31, 2013
Mundipharma [Member]
Jun. 30, 2013
Mundipharma [Member]
Reimbursed joint development cost [Member]
Jun. 30, 2013
Mundipharma [Member]
Reimbursed joint development cost [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                  
Potential milestone payments   $ 16,000,000 $ 107,000,000            
Deferred development cost 12,300,000                
Company determined development payment       7,000,000          
Development cost liability         18,700,000 18,700,000      
Development cost differential, maximum payment               15,000,000 15,000,000
License and contract revenue               268,000 589,000
Portion of joint development costs incurred by the parties         40.00%        
Potential portion of joint development costs incurred by the parties           50.00%      
Developmental cost differential amount             12,099    
Remaining developmental cost         18,700,000 18,700,000      
Fair value of related contingent payment obligation to research and development       0          
Difference in related contingent payment       2,400,000          
Accounts receivable         $ 24,000 $ 24,000