Condensed Consolidated Statements of Operations (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013	Jun. 30, 2012
Revenues:
Product sales, net	$ 32,213,000	$ 65,627,000	$ 61,559,000	$ 122,411,000
As Restated [Member]
Revenues:
Product sales, net	32,213,000	65,627,000	61,559,000	122,411,000
License and contract revenue	1,019,000	3,075,000	10,340,000	6,150,000
Total revenues	33,232,000	68,702,000	71,899,000	128,561,000
Operating costs and expenses:
Cost of product sales (excludes amortization of purchased intangible assets)	7,268,000	11,574,000	14,050,000	20,247,000
Selling, general and administrative	22,584,000	23,176,000	44,598,000	41,305,000
Research and development	104,660,000	9,288,000	22,343,000	17,819,000
Amortization and impairment of purchased intangibles	5,449,000	1,636,000	9,894,000	2,566,000
Total operating costs and expenses	45,761,000	45,674,000	90,885,000	81,937,000
(Loss) income from operations	(12,529,000)	23,028,000	(18,986,000)	46,624,000
Other income (expense), net	(163,000)	(1,507,000)	(1,481,000)	(1,369,000)
(Loss) income before income taxes	(12,692,000)	21,521,000	(20,467,000)	45,255,000
Benefit (provision) for income taxes	2,971,000	(3,171,000)	5,310,000	19,932,000
Net (loss) income	$ (9,721,000)	$ 18,350,000	$ (15,157,000)	$ 65,187,000
Net (loss) income per share:
Basic	$ (0.16)	$ 0.31	$ (0.26)	$ 1.11
Diluted	$ (0.16)	$ 0.29	$ (0.26)	$ 1.02
Weighted average shares outstanding:
Basic	58,977,295	58,763,700	58,995,735	58,617,530
Diluted	58,977,295	63,387,003	58,995,735	63,666,546