Balance Sheet Account Detail - Summary of Cash and Cash Equivalents and Marketable Securities (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Schedule of Investments [Line Items]
Historical or Amortized Cost	$ 0	$ 3,512
Historical or Amortized Cost	74,122	97,269
Equity securities	136	5,718
Cash, cash equivalents, and short-term investments	75,096	100,647
Level 1
Schedule of Investments [Line Items]
Equity securities	$ 136	5,718
Unicycive Therapeutics, Inc.
Schedule of Investments [Line Items]
Number of shares held in investment (in shares)	300,000
Number of shares sold (in shares)	600,000
Realized gain on equity securities	$ 500
Unicycive Therapeutics, Inc. | Level 1
Schedule of Investments [Line Items]
Equity securities	$ 100
CASI Common Stock
Schedule of Investments [Line Items]
Number of shares held in investment (in shares)	0
Number of shares sold (in shares)	900,000
Realized loss on equity securities	$ 1,900
Cash and Cash Equivalents
Schedule of Investments [Line Items]
Equity securities	0	0
Cash, cash equivalents, and short-term investments	40,368	88,539
Marketable Securities
Schedule of Investments [Line Items]
Equity securities	136	5,718
Cash, cash equivalents, and short-term investments	34,728	12,108
Money market funds
Schedule of Investments [Line Items]
Historical or Amortized Cost	36,298	66,322
Available-for-sale	36,298	66,322
Money market funds | Cash and Cash Equivalents
Schedule of Investments [Line Items]
Available-for-sale	36,298	66,322
Money market funds | Marketable Securities
Schedule of Investments [Line Items]
Available-for-sale	0	0
Government-related debt securities
Schedule of Investments [Line Items]
Historical or Amortized Cost	30,359
Available-for-sale	30,348
Government-related debt securities | Cash and Cash Equivalents
Schedule of Investments [Line Items]
Available-for-sale	0
Government-related debt securities | Marketable Securities
Schedule of Investments [Line Items]
Available-for-sale	30,348
Mutual funds
Schedule of Investments [Line Items]
Historical or Amortized Cost	3,395	5,218
Available-for-sale	4,244	6,390
Mutual funds | Cash and Cash Equivalents
Schedule of Investments [Line Items]
Available-for-sale	0	0
Mutual funds | Marketable Securities
Schedule of Investments [Line Items]
Available-for-sale	4,244	6,390
Bank deposits
Schedule of Investments [Line Items]
Historical or Amortized Cost	4,070	22,217
Available-for-sale	4,070	22,217
Bank deposits | Cash and Cash Equivalents
Schedule of Investments [Line Items]
Available-for-sale	4,070	22,217
Bank deposits | Marketable Securities
Schedule of Investments [Line Items]
Available-for-sale	$ 0	$ 0