Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash Flows From Operating Activities:
Loss from continuing operations	$ (44,447)	$ (85,613)
Loss from discontinued operations, net of income taxes	(43)	(216)
Net loss	(44,490)	(85,829)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	147	138
Stock-based compensation	5,088	8,572
Non-cash lease expense	724	766
Other non-cash items	183	188
Loss on disposal of assets	4	0
Realized gain on sale of equity holdings	(1,390)	(4,121)
Unrealized loss on equity holdings	5,488	12,387
Changes in operating assets and liabilities:
Accounts receivable, net	0	68
Other receivables	414	(1,063)
Prepaid expenses and other current assets	(2,735)	804
Other assets	834	(1)
Accounts payable and other accrued liabilities	(8,362)	5,933
Accrued payroll and benefits	(4,053)	(2,971)
Other long-term liabilities	(5,594)	988
Net cash used in operating activities	(53,742)	(64,141)
Cash Flows From Investing Activities:
Proceeds from maturities of investments	2,695	92,023
Proceeds from sale of equity holdings	985	4,062
Purchases of investments	(38,108)	(16,351)
Purchases of property and equipment, net	(45)	(140)
Net cash (used in) provided by investing activities	(34,473)	79,594
Cash Flows From Financing Activities:
Issuance of common shares to Hanmi Pharmaceutical Co., Ltd.	20,000	0
Proceeds from sale of common stock under an at-the-market sales agreement, net	4,947	52,622
Proceeds from sale of stock under our employee stock purchase plan	257	474
Proceeds from employees for exercises of stock options	0	2
Net cash provided by financing activities	25,204	53,098
Effect of exchange rates on cash and cash equivalents	(16)	13
Net (decrease) increase in cash and cash equivalents	(63,027)	68,564
Cash and cash equivalents—beginning of period	88,539	46,009
Cash and cash equivalents—end of period	25,512	114,573
Supplemental disclosure of cash flow information:
Cash paid for facility and equipment under operating leases	1,164	1,187
Cash paid for income taxes	$ 0	$ 12