Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Operating costs and expenses:
Selling, general and administrative	$ 60,406	$ 60,357
Research and development	87,297	109,377
Total operating costs and expenses	147,703	169,734
Loss from continuing operations before other income (expense) and income taxes	(147,703)	(169,734)
Other income (expense):
Interest income, net	163	1,342
Other expense, net	(10,892)	(2,940)
Total other expense	(10,729)	(1,598)
Loss from continuing operations before income taxes	(158,432)	(171,332)
(Provision) benefit for income taxes from continuing operations	(4)	60
Loss from continuing operations	(158,436)	(171,272)
Income (loss) from discontinued operations, net of income taxes	(192)	10,404
Net loss	$ (158,628)	$ (160,868)
Basic and diluted loss per share:
Loss per common share from continuing operations, basic (in dollars per share)	$ (1.02)	$ (1.38)
Loss per common share from continuing operations, diluted (in dollars per share)	(1.02)	(1.38)
Income per common share from discontinued operations, basic (in dollars per share)	0	0.08
Income per common share from discontinued operations, diluted (in dollars per share)	0	0.08
Net loss per common share, basic (in dollar per share)	(1.02)	(1.29)
Net loss per common share, diluted (in dollar per share)	$ (1.02)	$ (1.29)
Weighted average shares outstanding, basic (in shares)	154,861,704	124,386,545
Weighted average shares outstanding, diluted (in shares)	154,861,704	124,386,545