Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019
Cash Flows From Operating Activities:
Loss from continuing operations	$ (121,364)	$ (95,186)
Income from discontinued operations, net of income taxes	255	21,547
Net loss	(121,109)	(73,639)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	(105)	1,487
Stock-based compensation	13,371	17,205
Recognized gain on Commercial Product Portfolio Transaction	0	(33,451)
Non-cash lease expense	1,148	1,313
Amortization of discount on investments in debt securities	84	(348)
Realized gain on mutual funds	(136)	0
Income tax recognition on unrealized gain on available-for-sale securities	0	(31)
Realized gain on sale of equity holdings	(542)	(2,674)
Unrealized loss on equity holdings	16,029	9,745
Unrealized loss (gain) from transactions denominated in foreign currency	501	(5)
Change in deferred tax liabilities	0	(1,469)
Change in fair value of contingent consideration	0	1,478
Changes in operating assets and liabilities:
Accounts receivable, net	1	29,359
Other receivables	6,370	(4,068)
Inventories	0	(2,037)
Prepaid expenses and other current assets	(2,663)	(5,005)
Other assets	6	(1,428)
Accounts payable and other accrued liabilities	426	(35,233)
Accrued payroll and benefits	427	(3,378)
FOLOTYN development liability	0	(4)
Contract liabilities	0	(3,490)
Other long-term liabilities	(2,134)	2,234
Net cash used in operating activities	(88,326)	(103,439)
Cash Flows From Investing Activities:
Proceeds from Commercial Product Portfolio Transaction	0	158,765
Proceeds from maturities of marketable securities	92,433	38,540
Proceeds from sale of equity holdings	1,843	5,074
Proceeds from sale of mutual funds	2,496	0
Purchases of marketable securities	(71,671)	(127,584)
Purchases of mutual funds	(1,910)	0
Purchases of property and equipment, net	(6,991)	(8,670)
Net cash provided by investing activities	16,200	66,125
Cash Flows From Financing Activities:
Proceeds from sale of stock under our employee stock purchase plan	283	444
Proceeds from employees for exercises of stock options	13	6,355
Net cash provided by financing activities	84,931	8,616
Effect of exchange rates on cash, cash equivalents and restricted cash	(91)	(144)
Net increase (decrease) in cash, cash equivalents and restricted cash	12,714	(28,842)
Cash, cash equivalents and restricted cash—beginning of period	64,418	157,480
Cash, cash equivalents and restricted cash—end of period	77,132	128,638
Supplemental disclosure of cash flow information:
Cash paid for facility and equipment under operating leases	1,805	1,266
Cash paid for income taxes	14	38
Noncash investing activities:
Additions of property and equipment that remain in accounts payable and other accrued liabilities	6,017	300
Public offering
Cash Flows From Financing Activities:
Proceeds from issuance of common stock pursuant to at-the-market offering	69,733	0
At-the-market sales offering
Cash Flows From Financing Activities:
Proceeds from issuance of common stock pursuant to at-the-market offering	$ 14,902	$ 1,817