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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Cash Flows From Operating Activities:    
Loss from continuing operations $ (72,846) $ (68,629)
Income from discontinued operations, net of income taxes (Note 10) 189 20,975
Net loss (72,657) (47,654)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 282 1,400
Stock-based compensation (Note 4) 9,263 13,019
Recognized gain on Commercial Product Portfolio Transaction (Note 10) 0 (33,644)
Non-cash lease expense (Note 8(a)) 765 874
Unrealized gain on investments in debt securities and bank CDs (Note 3(a)) 0 133
Amortization of discount on investments in debt securities (Note 3(a)) 23 (331)
Realized gain on mutual funds (118) 0
Income tax recognition on unrealized gain on available-for-sale securities 0 (33)
Realized gain on sale of equity holdings (Note 7) (542) (2,674)
Unrealized loss on equity holdings (Note 3(a) and Note 7) 6,622 11,758
Unrealized loss (gain) from transactions denominated in foreign currency 508 (5)
Change in deferred tax liabilities 0 (1,469)
Change in fair value of contingent consideration (Note 8(b)) 0 1,478
Changes in operating assets and liabilities:    
Accounts receivable, net 0 27,314
Other receivables 3,257 (6,535)
Inventories 0 (2,037)
Prepaid expenses and other current assets (945) (3,164)
Other assets 401 (1,087)
Accounts payable and other accrued liabilities (3,277) (33,334)
Accrued payroll and benefits (1,812) (4,592)
FOLOTYN development liability 0 (4)
Contract liabilities 0 2,395
Other long-term liabilities (2,162) 1,843
Net cash used in operating activities (60,392) (76,349)
Cash Flows From Investing Activities:    
Proceeds from Commercial Product Portfolio Transaction (Note 1(b)) 0 158,765
Proceeds from maturities of marketable securities 88,263 0
Proceeds from sale of equity holdings (Note 7) 1,843 5,074
Proceeds from sale of mutual funds 2,380 0
Purchases of marketable securities (Note 3(a)) (8,998) (127,564)
Purchases of mutual funds (1,580) 0
Purchases of property and equipment, net (Note 3(b)) (4,066) (1,241)
Net cash provided by investing activities 77,842 35,034
Cash Flows From Financing Activities:    
Proceeds from employees for exercises of stock options 0 3,854
Proceeds from sale of common stock under an at-the-market sales agreement (Note 12) 3,071 1,814
Proceeds from sale of stock under our employee stock purchase plan 282 444
Net cash provided by financing activities 3,353 6,112
Effect of exchange rates on cash, cash equivalents and restricted cash (95) (6)
Net increase (decrease) in cash, cash equivalents and restricted cash 20,708 (35,209)
Cash, cash equivalents and restricted cash—beginning of period 64,418 157,480
Cash, cash equivalents and restricted cash—end of period 85,126 122,271
Supplemental disclosure of cash flow information:    
Cash paid for facility and equipment under operating leases 1,201 921
Cash paid for income taxes 14 33
Noncash investing activities:    
Additions of property and equipment that remain in accounts payable and other accrued liabilities (Note 3(b)) $ 324 $ 3,209