Consolidated Statements of Cash Flows $ in Thousands	12 Months Ended
	Dec. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)
Cash Flows From Operating Activities:
Loss from continuing operations	$ (135,386)	$ (126,706)	$ (100,752)
Income from discontinued operations, net of income taxes (Note 12)	22,697	5,965	8,563
Net loss	(112,689)	(120,741)	(92,189)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	1,620	28,409	27,972
Stock-based compensation (Note 4)	21,838	17,483	15,139
Recognized gain on Commercial Product Portfolio Transaction (Note 12)	(34,568)	0	0
Amortization of operating leases (Note 10(a))	1,715	0	0
Amortization of discount on investments in debt securities, recorded to interest income (Note 3(a))	(431)	0	0
Income tax benefit recognition on unrealized gain for available-for-sale securities	(205)	0	(9,651)
Realized gain on sale of CASI stock (Note 8)	(2,674)	0	0
Unrealized loss (gain) on CASI stock holdings (Note 3(a) and Note 8)	12,665	(10,458)	0
Unrealized (gain) loss from transactions denominated in foreign currency	(6)	10	(23)
Change in deferred taxes	(1,469)	31	(5,237)
Change in fair value of contingent consideration	1,478	(1,927)	4,957
Accretion of debt discount on 2018 Convertible Notes, recorded to interest expense (Note 9)	0	1,931	4,890
Amortization of deferred financing costs on 2018 Convertible Notes, recorded to interest expense (Note 9)	0	220	567
Bad debt expense (recovery)	(12)	12	(17)
Loss on 2018 Convertible Note purchase (Note 9)	0	0	845
Change in cash surrender value of corporate-owned life insurance policy	0	(5)	(418)
Changes in operating assets and liabilities:
Accounts receivable, net	29,420	2,844	7,694
Other receivables	(5,871)	(1,571)	3,663
Inventories	(2,037)	3,390	4,318
Prepaid expenses and other assets	(2,473)	(3,642)	(6,137)
Other assets	(1,188)	5,010	1,573
Accounts payable and other accrued liabilities	(35,769)	12,112	6,459
Accrued payroll and benefits	(2,168)	592	280
FOLOTYN development liability	(4)	(389)	(744)
Contract liabilities (Note 3(i))	(4,850)	4,850	0
Other long-term liabilities	3,047	(564)	(3,389)
Deferred revenue	0	0	593
Net cash used in operating activities	(134,631)	(62,403)	(38,855)
Cash Flows From Investing Activities:
Proceeds from Commercial Product Portfolio Transaction (Note 1(b))	158,571	0	0
Proceeds from maturities of marketable securities	77,475	0	0
Proceeds from sale of CASI stock (Note 8)	5,074	0	0
Purchase of investment securities available-for-sale (Note 3(a))	(200,160)	0	0
Purchases of property and equipment (Note 3(b))	(9,018)	(107)	(465)
Proceeds from sale of property and equipment	50	0	0
Proceeds from redemption of corporate-owned life insurance policy	0	4,130	0
Cash paid for KHAPZORY distribution rights	0	(2,650)	0
Payment for corporate-owned life insurance premiums	0	0	(601)
Purchase of equity securities (Note 8)	0	0	(15)
Net cash provided by (used in) investing activities	31,992	1,373	(1,081)
Cash Flows From Financing Activities:
Proceeds from employees for exercises of stock options	7,147	13,475	5,477
Proceeds from sale of stock under our employee stock purchase plan	663	1,122	1,010
Proceeds from sale of common stock under an at-the-market sales agreement (Note 5)	1,817	0	128,272
Proceeds from employees, for our remittance to tax authorities, upon vesting of restricted stock and upon exercises of stock options	0	4,645	0
Payments to tax authorities upon employees' surrender of restricted stock upon vesting and upon exercises of stock options	0	(27,679)	(4,331)
Payment of principal upon the maturity of the 2018 Convertible Notes (Note 9)	0	(20)	0
Purchase of 2018 Convertible Notes (Note 9)	0	0	(27,500)
Purchase of warrants related to the conversion hedge of 2018 Convertible Notes (Note 9)	0	0	(27,189)
Proceeds from sale of call options related to the conversion hedge of 2018 Convertible Notes (Note 9)	0	0	32,982
Net cash provided by (used in) financing activities	9,627	(8,457)	108,721
Effect of exchange rates on cash and equivalents	(50)	(356)	316
Net (decrease) increase in cash and cash equivalents	(93,062)	(69,843)	69,101
Cash and cash equivalents — beginning of year	157,480	227,323	158,222
Cash and cash equivalents — end of year		157,480	227,323
Supplemental Disclosure of Cash Flow Information:
Cash paid for facility and equipment under operating leases	1,835	0	0
Cash paid for income taxes	38	45	17
Cash paid for interest	0	1,031	2,692
Noncash investing activities:
Additions of property and equipment that remain in accounts payable and other accrued liabilities (Note 3(b))	2,760	0	$ 0
Cash and Cash Equivalents, at Carrying Value	$ 64,418	$ 157,480