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Income Taxes - Additional Information (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Taxes [Line Items]      
Benefit for income taxes from continuing operations $ 7,675 $ 1,902 $ 14,813
Valuation allowance 152,966 131,042  
Increase (decrease) in valuation allowance due to deferred tax assets 21,900 45,000  
Increase (decrease) in valuation allowance due to discontinued operations (2,000)    
Research and development tax credits 22,724 21,618  
Unrecognized tax benefits, if recognized, would affect the effective tax rate 100 $ 200 $ 200
Federal      
Income Taxes [Line Items]      
Net operating loss carryforwards 497,000    
Research and development tax credits 15,900    
State      
Income Taxes [Line Items]      
Net operating loss carryforwards 266,900    
Research and development tax credits 8,600    
Foreign      
Income Taxes [Line Items]      
Net operating loss carryforwards $ 5,200