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Balance Sheet Account Detail - Components of Intangible Assets Net of Accumulated Amortization (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
May 29, 2013
Nov. 30, 2018
Mar. 31, 2015
Dec. 31, 2018
Dec. 31, 2017
Product Rights [Line Items]          
Historical Cost       $ 308,318 $ 305,668
Accumulated Amortization       (185,132) (157,855)
Foreign Currency Translation       (3,409) (2,471)
Impairment       (8,183) (8,183)
Net Amount       111,594 137,159
MARQIBO IPR&D (NHL and further ALL indications) [Member]          
Product Rights [Line Items]          
Historical Cost       17,600 17,600
Accumulated Amortization       0 0
Foreign Currency Translation       0 0
Impairment       0 0
Net Amount       17,600 17,600
EVOMELA Distribution Rights [Member]          
Product Rights [Line Items]          
Historical Cost       7,700 7,700
Accumulated Amortization       (1,629) (1,037)
Foreign Currency Translation       0 0
Impairment       0 0
Net Amount       $ 6,071 6,663
Full Amortization Period (months)       156 months  
Remaining Amortization Period (months)       123 months  
KHAPZORY Distribution Rights [Member]          
Product Rights [Line Items]          
Historical Cost       $ 2,650  
Accumulated Amortization       (379)  
Foreign Currency Translation       0  
Impairment       0  
Net Amount       $ 2,271  
Full Amortization Period (months)       14 months  
Remaining Amortization Period (months)       12 months  
BELEODAQ distribution rights [Member]          
Product Rights [Line Items]          
Historical Cost       $ 25,000 25,000
Accumulated Amortization       (8,438) (6,563)
Foreign Currency Translation       0 0
Impairment       0 0
Net Amount       $ 16,562 18,437
Full Amortization Period (months)       160 months  
Remaining Amortization Period (months)       106 months  
MARQIBO distribution rights [Member]          
Product Rights [Line Items]          
Historical Cost       $ 26,900 26,900
Accumulated Amortization       (21,501) (17,182)
Foreign Currency Translation       0 0
Impairment       0 0
Net Amount       $ 5,399 9,718
Full Amortization Period (months)       81 months  
Remaining Amortization Period (months)       18 months  
FOLOTYN distribution rights [Member]          
Product Rights [Line Items]          
Historical Cost       $ 118,400 118,400
Accumulated Amortization       (67,187) (54,111)
Foreign Currency Translation       0 0
Impairment $ (1,000)     0 0
Net Amount       $ 51,213 64,289
Full Amortization Period (months)       152 months  
Remaining Amortization Period (months)       47 months  
ZEVALIN distribution rights [Member] | United States [Member]          
Product Rights [Line Items]          
Historical Cost       $ 41,900 41,900
Accumulated Amortization       (41,031) (37,557)
Foreign Currency Translation       0 0
Impairment       0 0
Net Amount       $ 869 4,343
Full Amortization Period (months)       123 months  
Remaining Amortization Period (months)       3 months  
ZEVALIN distribution rights [Member] | Ex-U.S. [Member]          
Product Rights [Line Items]          
Historical Cost       $ 23,490 23,490
Accumulated Amortization       (18,071) (17,232)
Foreign Currency Translation       (3,409) (2,471)
Impairment       0 0
Net Amount       $ 2,010 3,787
Full Amortization Period (months)       96 months  
Remaining Amortization Period (months)       15 months  
FUSILEV distribution rights [Member]          
Product Rights [Line Items]          
Historical Cost       $ 16,778 16,778
Accumulated Amortization       (9,618) (9,618)
Foreign Currency Translation       0 0
Impairment       (7,160) (7,160)
Net Amount       $ 0 0
Full Amortization Period (months)       56 months  
Remaining Amortization Period (months)       0 months  
FOLOTYN out-License [Member]          
Product Rights [Line Items]          
Historical Cost       $ 27,900 27,900
Accumulated Amortization       (17,278) (14,555)
Foreign Currency Translation       0 0
Impairment       (1,023) (1,023)
Net Amount       $ 9,599 $ 12,322
Full Amortization Period (months)       110 months  
Remaining Amortization Period (months)       43 months  
KHAPZORY [Member]          
Product Rights [Line Items]          
Milestone payments   $ 2,700      
Fusilev [Member]          
Product Rights [Line Items]          
Impairment     $ (7,200)