Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Revenue:
Total revenues	$ 25,268	$ 36,395	$ 79,930	$ 99,797
Operating costs and expenses:
Selling, general and administrative	19,837	18,527	67,393	55,052
Research and development	21,060	13,815	60,442	43,760
Amortization of intangible assets	6,923	6,928	20,804	20,718
Total operating costs and expenses	54,292	51,449	168,530	155,369
Loss from operations	(29,024)	(15,054)	(88,600)	(55,572)
Other (expense) income:
Interest expense, net	(12)	(2,014)	(484)	(6,196)
Change in fair value of contingent consideration related to acquisitions	1,200	(2,942)	717	(3,236)
Other (expense) income, net	(40,880)	251	17,583	901
Total other (expense) income	(39,692)	(4,705)	17,816	(8,531)
Loss before income taxes	(68,716)	(19,759)	(70,784)	(64,103)
(Provision) benefit for income taxes	(2)	1,466	(8)	1,412
Net loss	$ (68,718)	$ (18,293)	$ (70,792)	$ (62,691)
Net loss per share:
Basic ($ per share)	$ (0.66)	$ (0.22)	$ (0.69)	$ (0.78)
Diluted ($ per share)	$ (0.66)	$ (0.22)	$ (0.69)	$ (0.78)
Weighted average shares outstanding:
Basic (shares)	104,106,295	83,463,153	102,571,850	80,177,370
Diluted (shares)	104,106,295	83,463,153	102,571,850	80,177,370
Product [Member]
Revenue:
Total revenues	$ 24,556	$ 31,234	$ 76,419	$ 88,235
Operating costs and expenses:
Cost of sales and service revenue	6,472	12,179	19,891	31,618
License and Service [Member]
Revenue:
Total revenues	712	5,161	3,511	11,562
Service [Member]
Operating costs and expenses:
Cost of sales and service revenue	$ 0	$ 0	$ 0	$ 4,221