FOLOTYN License Agreement And Development Liability - Schedule of Drug Development Liability Adjustments (Detail) $ in Thousands	9 Months Ended
	Sep. 30, 2017 USD ($)
Accrued Drug Development Expenses [Roll Forward]
Balance at December 31, 2016	$ 861
Balance at September 30, 2017	153
FOLOTYN [Member]
Accrued Drug Development Expenses [Roll Forward]
Balance at December 31, 2016	13,130
Transfer from long-term to current in 2017	0
(Less): Expenses incurred in 2017	(704)
Balance at September 30, 2017	12,426
FOLOTYN [Member] | Development Liability, Current [Member]
Accrued Drug Development Expenses [Roll Forward]
Balance at December 31, 2016	861
Transfer from long-term to current in 2017	(4)
(Less): Expenses incurred in 2017	(704)
Balance at September 30, 2017	153
FOLOTYN [Member] | Development Liability, Long Term [Member]
Accrued Drug Development Expenses [Roll Forward]
Balance at December 31, 2016	12,269
Transfer from long-term to current in 2017	4
(Less): Expenses incurred in 2017	0
Balance at September 30, 2017	$ 12,273