EXHIBIT 10.4.2

                  LEASE ADDENDUM THREE FOR MODIFICATION OF RENT

THIS ADDENDUM DATED February 12, 2004 shall be attached and considered  apart of
that certain Lease Agreement  entered into by and between James M. Roswell d/b/a
Burbank East Business Park, ("Landlord"), and Biopool International,  Inc. d/b/a
Xtrana,  Inc., a Delaware  Corporation  ("tenant"),  dated December 19, 2000, as
modified by the Lease  Addendum  One for  Increase in Space dated  December  21,
2001,  and Lease  Addendum  Two for  Modification  of Rent and  Option for Early
Termination  dated November 11, 2003.  For the promises  contained  herein,  and
other good and valuable consideration,  the receipt and sufficiency of which are
hereby acknowledged, the parties agree as follows.

The following  provisions shall hereby modify the aforementioned Lease Agreement
as modified by Lease Addendum One for Increase in Space dated December 21, 2001,
and Lease Addendum Two for Modification of Rent and Option for Early Termination
dated November 11, 2003.

The Section 1 of the Lease Addendum Two entitled Gross Rent Abatement,  shall be
replaced in its entirety with the following:

1.       GROSS RENT  ABATEMENT.  Landlord and Tenant agree to a 6 month  partial
         abatement  of the Gross  Rent in the amount of $5,000 per month for a 6
         month period  commencing  on December 1, 2003,  and expiring on May 31,
         2004.  During this abatement time period,  Tenant shall pay Landlord as
         Gross Rent the sum of fourteen  thousand,  eight  hundred,  thirty nine
         dollars and 75/100  ($14,839.75)  on or before  December 1, 2003, and a
         like  sum on or  before  the  first  day of each and  every  successive
         calendar month  thereafter  and expiring  March 31, 2004.  Landlord and
         Tenant agree that  commencing on April 1, 2004, and expiring on May 31,
         2004,  Tenant shall pay Landlord Gross Rent the sum of twelve thousand,
         one hundred, one dollars and 22/100 ($12,101.22).

It is hereby agreed and  understood  between  Landlord and Tenant that all other
terms and  conditions  of the  Lease  Agreement  and  attachments,  addenda  and
exhibits thereto, shall be unmodified and shall remain in full force and effect.



LANDLORD:                                      TENANT:

James M. Roswell d/b/a                         Biopool International, Inc. d/b/a
Burbank East Business Park                     Xtrana, Inc.


By: /s/ James M. Roswell                       By: /s/ Timothy J. Dahltorp
   ----------------------------                   ------------------------------
        James M. Roswell                               Timothy J. Dahltorp
                                                       Chief Executive Officer

Date: February 12, 2004                        Date: February 12, 2004