<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2017-05-15</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000829323</issuerCik>
        <issuerName>Inuvo, Inc.</issuerName>
        <issuerTradingSymbol>INUV</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000883961</rptOwnerCik>
            <rptOwnerName>TOCQUEVILLE ASSET MANAGEMENT L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>40 WEST 57TH STREET</rptOwnerStreet1>
            <rptOwnerStreet2>19TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2017-05-15</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>15790</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.19</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2181943</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F3"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Charles D. Morgan</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">(I) The reported shares are in accounts of clients of Tocqueville Asset Management, L.P. (The &quot;Reported Person&quot;). The Reporting Person may be deemed to be the beneficial owner of the reported shares. The Reporting Person disclaims beneficial ownership of the reported shares except to the extend of his or its pecuniary interest therein, and his report shall not be deemed an admission that such Reporting Person is the beneficial owner of the securities for purposes of Section 16 of Securities Exchange Act of 1934, as amended, or for any other purpose.</footnote>
        <footnote id="F2">Charles D. Morgan, a related person of Tocqueville Asset Management, L.P., serves as a Director of Inuvo, Inc. Rich Howe, an advisory client of Tocqueville Asset Management, L.P., serves as Chairman and CEO of Inuvo, Inc.</footnote>
        <footnote id="F3">On May 15, 2017, 15,790 shares of Inuvo, Inc. were transferred into advisory accounts of Tocqueville Asset Management, L.P.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Victor Huwang</signatureName>
        <signatureDate>2017-05-17</signatureDate>
    </ownerSignature>
</ownershipDocument>
