Accelerated Share Repurchases, Authorized Amount

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- Definition

Accelerated Share Repurchases, Shares Received

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- Definition

Fair Value Adjustment On Accelerated Share Repurchases

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- Definition

Share-Based Compensation Arrangement By Share-Based Payment Award, Award Vesting Rights, Number Of Milestones

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- Definition

Share-Based Compensation Arrangement By Share-Based Payment Award, Award Vesting Rights, Number Of Milestones Required To Be Met

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- Definition

Share-Based Compensation Arrangement By Share-based Payment Award, Fair Value Assumptions, Expected Achievement Rate

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- Definition

Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercised, Intrinsic Value

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- Definition

The price paid per share to immediately purchase the targeted number of shares on the date of executing the accelerated share repurchase agreement.

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-Name Accounting Standards Codification
-Topic 505
-SubTopic 30
-Section 25
-Paragraph 5
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- Definition

Amount of cash receipt from (payment to) bank; or stock received from (issuance to) bank in the settlement of the accelerated share repurchase agreement.

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- Definition

Aggregate number of common shares reserved for future issuance.

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- Definition

Weighted-average period over which cost not yet recognized is expected to be recognized for award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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- Definition

Amount of cost to be recognized for nonvested award under share-based payment arrangement. Excludes share and unit options.

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- Definition

Amount of cost to be recognized for option under share-based payment arrangement.

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- Definition

The cash outflow to reacquire common stock during the period.

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-Publisher FASB
-Name Accounting Standards Codification
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- Definition

Period over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, combination of market, performance or service condition.

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- Definition

The number of equity-based payment instruments, excluding stock (or unit) options, that were forfeited during the reporting period.

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- Definition

The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

+ References

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- Definition

The weighted average fair value at grant date for nonvested equity-based awards issued during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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- Definition

The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term.

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- Definition

The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period.

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- Definition

The risk-free interest rate assumption that is used in valuing an option on its own shares.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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No definition available.

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- Definition

Number of additional shares authorized for issuance under share-based payment arrangement.

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No definition available.

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- Definition

The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.

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- Definition

Amount by which the current fair value of the underlying stock exceeds the exercise price of options outstanding.

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- Definition

Percentage of vesting of award under share-based payment arrangement.

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- Definition

Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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- Definition

Amount of stock repurchase plan authorized.

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No definition available.

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- Definition

Number of shares that have been repurchased during the period and are being held in treasury.

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Common Stock and Stock-Based Compensation - Narrative (Details)			3 Months Ended	12 Months Ended			17 Months Ended	65 Months Ended
	Sep. 24, 2020 USD ($) $ / shares shares	Aug. 04, 2015 shares	Mar. 31, 2021 milestone $ / shares shares	Dec. 31, 2021 USD ($) $ / shares shares	Dec. 31, 2020 USD ($) $ / shares shares	Dec. 31, 2019 USD ($) $ / shares shares	Mar. 17, 2020 USD ($)	Dec. 31, 2021 USD ($) shares	Sep. 23, 2020 USD ($)
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Repurchases of common stock				$ 21,213,000	$ 34,999,000	$ 17,961,000
Fair value adjustments on settled accelerated share repurchase agreement				$ 0	$ 2,962,000	$ 0
Shares of common stock repurchased (in shares) \| shares				429,446	774,489	317,429
Share-based payment award, award vesting period				4 years
Number of shares available for grant (in shares) \| shares				1,934,193				1,934,193
Weighted-average grant-date fair value of options granted (in dollars per share) \| $ / shares				$ 23.62	$ 28.98	$ 22.18
Unrecognized compensation cost				$ 8,853,000				$ 8,853,000
Total intrinsic value of options exercised				$ 2,434,000
Weighted average contractual terms of options outstanding				5 years 2 months 12 days	6 years 1 month 6 days	6 years 9 months 18 days
Aggregate pre-tax intrinsic value of options outstanding				$ 13,800,000	$ 11,600,000	$ 31,900,000		13,800,000
Common stock
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based payment award, number of additional shares authorized (in shares) \| shares		500,000
Options
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Unrecognized compensation cost expense term				2 years
Expected volatility						40.83%
Expected dividend yield				0.00%	0.00%	0.00%
Options \| Minimum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected term (in years)				5 years 6 months	5 years 6 months	1 year 6 months 3 days
Options \| Maximum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected term (in years)				6 years 29 days	6 years 29 days	9 years 4 months 28 days
RSU
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Unrecognized compensation cost expense term				2 years 3 months 18 days
Unrecognized compensation cost				$ 7,562,000				7,562,000
Expired (in shares) \| shares				76,167	79,849
Granted (in shares) \| shares				106,600	236,450
Granted (in dollars per share) \| $ / shares				$ 48.55	$ 59.48
PSU
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expired (in shares) \| shares			97,750	119,450	18,431
Granted (in shares) \| shares				159,000	0
Granted (in dollars per share) \| $ / shares				$ 62.94	$ 0
Risk free interest rate			0.18%
Expected volatility			44.00%
Expected term (in years)			3 years
Expected dividend yield			0.00%
PSU \| S&P Biotechnology
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Granted (in shares) \| shares			99,500,000
Granted (in dollars per share) \| $ / shares			$ 71.09
Milestone Performance-Based Stock Units
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Granted (in shares) \| shares			59,500
Granted (in dollars per share) \| $ / shares			$ 49.32
Number of milestones \| milestone			1
Number of milestones required to be met \| milestone			3
Expiration period			3 years
Expected achievement rate				0.00%
Milestone Performance-Based Stock Units \| Minimum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Award vesting percentage of target number granted			0.00%
Milestone Performance-Based Stock Units \| Maximum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Award vesting percentage of target number granted			200.00%
March 2020 Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock repurchase program, authorized amount (up to)							$ 160,000,000
Accelerated share repurchases, authorized amount									$ 25,000,000
Accelerated share repurchases, payment	$ 25,000,000
Accelerated share repurchases, shares received (in shares) \| shares	550,623
Accelerated share repurchases, initial price paid per share (in dollars per share) \| $ / shares	$ 45.40
Fair value adjustments on settled accelerated share repurchase agreement					$ 3,000,000
October 2018 Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Repurchases of common stock							$ 68,000,000
Accelerated Share Repurchase
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Repurchases of common stock								$ 228,100,000
Shares of common stock repurchased (in shares) \| shares								4,111,622