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Income Taxes
12 Months Ended
Dec. 31, 2021
Income Tax Disclosure [Abstract]  
Income Taxes Income Taxes
The components of our provision from income taxes is as follows:
 Year Ended December 31,
 202120202019
Current:
     Federal $6,912 $10,140 $6,689 
     State785 2,059 844 
$7,697 $12,199 $7,533 
Deferred:
     Federal (3,030)(1,227)392 
     State(588)(284)(240)
$(3,618)$(1,511)$152 
Provision for income taxes$4,079 $10,688 $7,685 

The reconciliation of the statutory U.S. Federal income tax rate to the Company's effective income tax rate is as follows;
 Year Ended December 31,
 202120202019
U.S. Federal statutory tax rate21 %21 %21 %
State income taxes, net of federal benefit (1)%%%
Tax effect on stock option exercises, net of forfeitures(44)%%%
R&D tax credits and Orphan Drug credits31 %(2)%(2)%
Limitation on executive compensation(60)%%10 %
Change in valuation allowance (40)%%%
Foreign rate differential%(1)%(2)%
Other (1)%%%
Effective tax rate(90)%47 %35 %
    

The effective tax rate for the year ended December 31, 2021, reflects certain non-deductible executive compensation, tax effect on stock option exercises, net of forfeitures and valuation allowance established on the deferred tax asset for an unrealized capital loss in our investment in Tyme partially offset by credits for research and development activities.
Deferred income taxes reflect the net tax effects of temporary differences between the carrying amount of assets and liabilities for financial reporting and the amounts used for income tax purposes. Significant components of the Company's deferred tax assets were as follows:
  December 31,
  2021 2020
Deferred tax assets  
   Net operating loss carryforward$1,563 $841 
   Stock based compensation 10,405 12,015 
   Other asset - equity investment with readily determined fair value3,190 1,771 
   Inventories 2,123 2,338 
   Employee-related expenses 1,240 51 
   Intangible assets 4,207 708 
   Right-of-use liability962 1,154 
   R&D tax credit carryforwards329 86 
   Other 1,489 1,216 
  Total deferred tax assets25,508 20,180 
Deferred tax liabilities 
   Installment sale - Malta485 483 
   Prepaid expenses45 43 
   Fixed assets 300 315 
   Lease liability921 1,092 
  Total deferred tax liabilities1,751 1,933 
  Valuation allowance (4,959)(3,067)
Net deferred tax assets$18,798 $15,180 

In July 2006, the Financial Accounting Standards Board (“FASB”) issued ASC 740-10, Uncertainty in Income Taxes, which defines the threshold for recognizing the benefits of tax-return positions in the financial statements as “more-likely-than-not” to be sustained by the taxing authorities. This statement also requires explicit disclosure requirements about a Company’s uncertainties related to their income tax position, including a detailed roll forward of tax benefits taken that do not qualify for financial statement recognition.

The Company files income tax returns in the U.S. federal jurisdiction and several states. The Company is under audit by the Internal Revenue Service and three states tax jurisdiction as of December 31, 2021. The Company has no amount recorded for any unrecognized tax benefits as of December 31, 2021. The Company regularly evaluates its tax positions for additional unrecognized tax benefits and associated interest and penalties, if applicable. There are many factors that are considered when evaluating these tax positions including: interpretation of tax laws, recent tax litigation on a position, past audit or examination history, and subjective estimates and assumptions.
As of December 31, 2021, the Company has a net operating loss ("NOL") carryforward in Malta of $4.5 million which has no expiration date and can be carried forward indefinitely until utilized.