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Balance Sheet Accounts
 12 Months Ended
Dec. 31, 2021
Balance Sheet Related Disclosures [Abstract]  
Balance Sheet Accounts Balance Sheet Accounts
Prepaid expenses and Other Current Assets
Prepaid and other current assets consist of the following:
December 31,
20212020
Advances to commercial manufacturers$942 $660 
Prepaid FDA user fee and advances to CROs1,108 1,262 
Prepaid insurance196 191 
Prepaid income taxes1,173 — 
Convertible promissory note, net5,312 — 
All other3,159 1,605 
Total Prepaid expenses and other current assets$11,890 $3,718 

Accrued Expenses and Other Liabilities
Accrued expenses and other liabilities consist of the following:
December 31,
20212020
Royalties payable to commercial partners$5,085 $5,996 
Accrued research & development4,100 2,724 
Accrued professional fees2,013 2,370 
Accrued salary and other compensation8,466 4,686 
Accrued product sales reserves4,390 4,966 
Current portion of lease liability1,309 1,123 
All other6,975 1,952 
Total Accrued expenses and other liabilities$32,338 $23,817 

Leases
We lease office space in Woodcliff Lake, New Jersey for our principal office under an amended lease agreement through June 2025. We also lease a lab space in Cambridge, Massachusetts under a lease agreement through April 2024, and a new office space located in Palm Beach Gardens, FL. The new lease agreement commenced on November 1, 2021 and will expire 36 months from the lease commencement date, which is October 31, 2024. All of our leases are classified as operating leases and have remaining lease terms of approximately 3.1 years. The principal office and the lab space leases include renewal options to extend the lease for up to 5 years. Furthermore, we have not elected the practical expedient to separate lease and non-lease components for all classes of underlying assets.
The table below summarizes the Company's total lease costs included in the consolidated financial statements, as well as other required quantitative disclosures (in thousands):

As of December 31,
July 13, 1905July 12, 1905
Operating lease cost$1,407 $1,323 
Total lease cost$1,407 $1,323 
Other information:
Cash paid for amounts included in the measurement of lease liabilities
     Operating cash flows for operating leases$1,407 $1,323 
Right-of-use assets obtained in exchange for new operating lease liabilities$270 $855 
Weighted-average remaining lease term - operating leases 3.1 years4.1 years
Weighted-average discount rate - operating leases 6.0 %6.0 %

Year Ending December 31,Operating Leases
20221,423 
20231,455 
20241,038 
2025413 
Thereafter— 
Total4,329 
     Less: present value discount(116)
Present value of lease liabilities$4,213 
Balance Sheet Classification as of December 31, 2021
Current lease liabilities (included with Accrued expenses and other liabilities)$1,309 
Long-term lease liabilities (included with Other long-term liabilities)2,904 
Total lease liabilities$4,213