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Balance Sheet Accounts
12 Months Ended
Dec. 31, 2019
Balance Sheet Related Disclosures [Abstract]  
Balance Sheet Accounts Balance Sheet Accounts
Prepaid and Other Current Assets
Prepaid and other current assets consist of the following:
 
December 31,
 
2019
 
2018
Advances to commercial manufacturers
$
2,462

 
$
2,700

Prepaid FDA user fee
6,345

 
1,540

Prepaid insurance
191

 
150

Prepaid income taxes
4,661

 
5,739

All other
1,445

 
134

Total Prepaid expenses and other current assets
$
15,104

 
$
10,263


Accrued Expenses and Other Liabilities
Accrued expenses and other liabilities consist of the following:
 
December 31,
 
2019
 
2018
Accrued expenses
 
 
 
Royalties payable to commercial partners
$
6,004

 
$
7,139

Accrued research & development
1,686

 
1,245

Accrued professional fees
1,926

 
2,408

Accrued salary and other compensation
8,083

 
5,049

Accrued product costs
8,364

 
5,869

All other
2,298

 
1,809

Total Accrued expenses and other liabilities
$
28,361

 
$
23,519



Adoption of FASB ASU No. 2016-02, “Leases (Topic 842)” as of January 1, 2019
The Company leases its corporate office under an amended lease agreement that expires on June 30, 2025 (the "Corporate Office Lease"). The Corporate Office Lease was amended on August 8, 2019 to extend the term through such date and to increase the amount of leased office space. The Company also leases lab space under a lease agreement that expires on October 31, 2023 (the "Lab Space Lease"). The Company estimated the right of use asset and the corresponding lease liability, on a discounted basis, as of the adoption date of January 1, 2019. The future minimum lease payments under this Corporate Office Lease are approximately $4.0 million.
For the Company's two operating leases (the Corporate Office Lease and Lab Space Lease), the depreciation and interest expense components are combined and recognized ratably over the remaining term of the lease as research and development and selling, general and administrative in the Company's consolidated statements of operations, respectively.
The Company used its estimated incremental borrowing rate to calculate the present value of the ROU assets and lease liabilities as of the date of adoption date. The implicit interest rate related to the Company’s two lease agreements was not known as of the date of adoption. Therefore, the Company calculated an incremental borrowing rate based on the rate of interest that the Company would have to pay to borrow on a collateralized basis over a similar term and amount equal to the lease payments in a similar economic environment.
Lease related disclosures consist of the following:
 
December 31,
 
2019
Right of use (ROU) asset, net included in Other assets
$
3,716

Lease liability included with Other long-term liabilities
$
3,000

Lease liability included with Accrued expenses and other liabilities
$
1,101

YTD 2019 depreciation of ROU asset
$
1,159

YTD 2019 related rent expense
$
1,146

YTD operating cash flows from operating leases
$
952

YTD operating lease costs
$
1,146

Weighted-average remaining lease term - operating leases
5.0 years

Weighted-average discount rate - operating leases
6
%


As of December 31, 2019, the future minimum lease commitments for the Company's two leases were as follows:
 
Total
 
2020
 
2021
 
2022
 
2023
 
2024
 
Beyond
 
$
6,607

 
$
1,345

 
$
1,362

 
$
1,376

 
$
1,291

 
$
820

 
$
413



As of December 31, 2018, the future minimum lease commitments for the Company's two leases were as follows:
 
Total
 
2019
 
2020
 
2021
 
2022
 
2023
 
$
3,661

 
$
1,146

 
$
864

 
$
583

 
$
583

 
$
485