X0306 4 2017-05-09 0 0000827809 NOVELION THERAPEUTICS INC. NVLN 0001684239 Buono Linda C/O NOVELION THERAPEUTICS INC. 887 GREAT NORTHERN WAY, SUITE 250 VANCOUVER A1 V5T 4T5 BRITISH COLUMBIA, CANADA 0 1 0 0 Sr. VP, Human Resources Common Shares 2017-05-09 4 M 0 274 A 274 D Common Shares 2017-05-09 4 F 0 93 9.42 D 181 D Restricted Stock Units 2017-05-09 4 M 0 274 0.00 D Common Shares 274 546 D Reflects a one-for-five share consolidation of the common shares of the Issuer effective December 16, 2016. Each restricted stock unit represents a contingent right to receive one common share. The shares reported as disposed were withheld by the Issuer to satisfy tax withholding obligations of the Reporting Person. 33.34% of the grant vested on May 9, 2017. Subject, with limited exceptions, to the Reporting Person's continued employment with the Issuer or one of its affiliates, 33.33% of the grant will vest on May 9, 2018 and 33.33% of the grant will vest on May 9, 2019. /s/ Jennifer Fitzpatrick, attorney-in-fact 2017-05-11