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Description of Business and Basis of Presentation (Details)
3 Months Ended
Mar. 31, 2019
USD ($)
product
Mar. 31, 2018
USD ($)
Jan. 01, 2019
USD ($)
Dec. 31, 2018
USD ($)
Nov. 08, 2018
USD ($)
Debt Instrument [Line Items]          
Number of commercial products | product 2        
Net loss $ 31,847,000 $ 32,828,000      
Net cash inflow from operating activities 8,150,000 $ (22,731,000)      
Short-term debt 73,928,000     $ 73,677,000  
Operating lease right-of-use asset 1,300,000        
Operating lease liability 1,335,000        
Intercompany Loan          
Debt Instrument [Line Items]          
Short-term debt         $ 3,500,000
Secured Debt | Bridge Credit Agreement          
Debt Instrument [Line Items]          
Loan aggregate amount 74,400,000        
Secured Debt | Intercompany Loan          
Debt Instrument [Line Items]          
Short-term debt 35,700,000        
Convertible Notes          
Debt Instrument [Line Items]          
Principal amount of convertible notes $ 302,500,000        
Debt instrument, stated interest rate percentage 2.00%        
Loan aggregate amount $ 302,498,000     $ 302,498,000  
ASU 2016-02          
Debt Instrument [Line Items]          
Operating lease right-of-use asset     $ 1,800,000    
Operating lease liability     $ 1,800,000