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Selected Quarterly Financial Data (unaudited) (Tables)
 12 Months Ended
Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]  
Schedule of Selected Quarterly Financial Data (unaudited)
The following table contains quarterly financial information for the years ended 2017 and 2016.

 
Quarter Ended
 
December 31, 2017
 
September 31, 2017
 
June 30, 2017
 
March 31, 2017
 
(in thousands, except per share amounts)
Net revenues
$
38,908

 
$
28,669

 
$
40,877

 
$
29,984

Cost of product sales
16,993

 
29,505

 
14,277

 
16,445

Loss from operations
(13,964
)
 
(39,399
)
 
(11,772
)
 
(21,663
)
Net loss
(24,568
)
 
(49,744
)
 
(21,436
)
 
(30,962
)
Net loss per common share - basic and diluted
(1.32
)
 
(2.67
)
 
(1.15
)
 
(1.67
)
 
 
 
 
 
 
 
 
 
Quarter Ended
 
December 31, 2016
 
September 31, 2016
 
June 30, 2016
 
March 31, 2016
 
(in thousands, except per share amounts)
Net revenues
$
13,574

 
$
—

 
$
—

 
$
—

Cost of product sales
5,971

 
—

 
—

 
—

Loss from operations
(14,360
)
 
(6,017
)
 
(7,403
)
 
(8,926
)
Net loss
(19,920
)
 
(5,936
)
 
(5,120
)
 
(21,894
)
Net loss per common share - basic and diluted
(1.48
)
 
(0.55
)
 
(0.50
)
 
(2.05
)