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Accrued Liabilities (Tables)
12 Months Ended
Dec. 31, 2017
Payables and Accruals [Abstract]  
Schedule of Accrued Liabilities
Accrued liabilities as of December 31, 2017 and 2016 consist of the following:
 
December 31,
 
2017
 
2016
 
(in thousands)
Accrued employee compensation and related costs
$
7,755

 
$
7,920

Accrued professional fees
4,118

 
3,466

Accrued sales allowances
13,471

 
7,849

Accrued royalties
3,588

 
3,301

Other accrued liabilities
12,906

 
14,644

Total
$
41,838

 
$
37,180

Schedule of Combined Activity in Sales Allowances and Reserves
The following table summarizes combined activity for lomitapide and metreleptin in the sales allowance and reserve for the years ended December 31, 2017 and 2016. There was no sales allowance in 2015 as the Company did not have any commercial products and did not generate any revenues.
 
December 31,
 
2017
 
2016
 
(in thousands)
Beginning balance
$
7,849

 
$

Provision
23,087

 
7,849

Payments
(17,465
)
 

Ending balance
$
13,471

 
$
7,849

Schedule of Restructuring Charges and Payments
The following table sets forth the components of the restructuring charge and payments made against the reserve for the year ended December 31, 2017

 
December 31, 2017
 
(in thousands)
Beginning restructuring balance
$

Costs incurred
2,536

Cash paid
(2,788
)
Other adjustments
262

Ending restructuring balance
$
10