Unaudited Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Income Statement [Abstract]
Net revenues	$ 40,877	$ 0	$ 70,861	$ 0
Cost of product sales	14,277	0	30,722	0
Operating expenses
Selling, general and administrative	26,514	4,474	50,965	10,410
Research and development	10,824	2,929	20,124	5,919
Restructuring charges	1,034	0	2,485	0
Total operating expenses	38,372	7,403	73,574	16,329
Loss from operations	(11,772)	(7,403)	(33,435)	(16,329)
Interest (expense) income, net	(9,613)	54	(18,825)	129
Fair value gain (loss) on investment	0	2,256	0	(10,704)
Other income (expense), net	75	(22)	127	(99)
Loss before provision for income taxes	(21,310)	(5,115)	(52,133)	(27,003)
Provision for income taxes	(126)	(5)	(265)	(11)
Net loss	$ (21,436)	$ (5,120)	$ (52,398)	$ (27,014)
Net loss per common share—basic and diluted (in usd per share)	$ (1.15)	$ (0.48)	$ (2.82)	$ (2.56)
Weighted-average shares outstanding—basic and diluted (in shares)	18,609	10,565	18,575	10,565