Consolidated Statements of Operations shares in Thousands, $ in Thousands		12 Months Ended
		Dec. 31, 2016 USD ($) $ / shares shares	Dec. 31, 2015 USD ($) $ / shares shares	Dec. 31, 2014 USD ($) $ / shares shares
Income Statement [Abstract]
Net product sales		$ 13,574	$ 0	$ 0
Cost of product sales		5,971	0	0
Operating expenses
Selling, general and administrative		29,525	16,222	17,682
Research and development		14,784	9,790	13,803
Restructuring charges		0	0	744
Termination Fee (Note 3)		0	(2,667)	(28,400)
Total operating expenses		44,309	23,345	3,829
Loss from operations		(36,706)	(23,345)	(3,829)
Interest (expense) income, net		(2,960)	277	113
Fair value loss on investment (Note 4)		(10,740)	0	0
Other income (expense), net		(1,999)	81	(481)
Loss from continuing operations before income taxes		(52,405)	(22,987)	(4,197)
Provision for Income tax (expense) recovery (Note 13)		(465)	(22)	192
Loss from continuing operations		(52,870)	(23,009)	(4,005)
Loss from discontinued operations, net of income taxes		0	0	(66)
Net loss		$ (52,870)	$ (23,009)	$ (4,071)
Basic and diluted net loss per common share
Continuing operations (in dollars per share) | $ / shares	[1]	$ (4.69)	$ (2.20)	$ (0.40)
Discontinued operation (in dollars per share) | $ / shares	[1],[2]	0.00	0.00	0.00
Net loss per common share (in dollars per share) | $ / shares	[1]	$ (4.69)	$ (2.20)	$ (0.40)
Weighted-average shares outstanding—basic and diluted (thousands)
Basic and diluted (in shares) | shares	[1]	11,284	10,434	10,225

[1] Amounts have been retroactively restated for all prior periods presented to reflect the one-for-five share consolidation of the Company’s common stock effected on December 16, 2016

[2] Rounded to zero.