SEWARD & KISSEL LLP

901 K Street, N.W.

Washington, DC 20001

Telephone: (202) 737-8833

Facsimile: (202) 737-5184

www.sewkis.com

March 28, 2013

Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Re: AllianceBernstein Variable Products Series Fund, Inc.

– AllianceBernstein Growth Portfolio (the “Portfolio”)

File Nos. 33-18647 and 811-05398

Accession No. 0001193125-13-106511

Dear Sir or Madam:

On behalf of the Registrant and pursuant to Rule 497(e) under the Securities Act of 1933, as amended, we hereby submit exhibits containing interactive data format risk/return summary information for the Portfolio. The purpose of this filing is to submit the XBRL information from the 497(e) filing dated March 14, 2013 for the Portfolio.

Please call me at the above-referenced number if you have any questions regarding the attached.

Sincerely,

/s/ Joanne A. Skerrett

Joanne A. Skerrett

Attachment

Index to Exhibits

Exhibit No.	Description of Exhibits
EX-101.INS	XBRL Instance Document
EX-101.SCH	XBRL Taxonomy Extension Schema Document
EX-101.CALC	XBRL Taxonomy Extension Calculation Linkbase
EX-101.DEF	XBRL Taxonomy Extension Definition Linkbase
EX-101.LAB	XBRL Taxonomy Extension Labels Linkbase
EX-101.PRE	XBRL Taxonomy Extension Presentation Linkbase