SEWARD & KISSEL LLP
                               901 K Street, N.W.
                                   Suite 800
                             Washington D.C. 20001

                           Telephone: (202) 737-8833
                           Facsimile: (202) 737-5184


                                                 May 6, 2015

VIA EDGAR
----------
Securities and Exchange Commission
100 F Street, N.E.
Washington, D.C.  20549

                 AB Variable Products Series Fund, Inc.
                 o    AB Intermediate Bond Portfolio
                 o    AB Large Cap Growth Portfolio
                 o    AB Growth and Income Portfolio
                 o    AB Growth Portfolio
                 o    AB International Growth Portfolio
                 o    AB Global Thematic Growth Portfolio
                 o    AB Small Cap Growth Portfolio
                 o    AB Real Estate Investment Portfolio
                 o    AB International Value Portfolio
                 o    AB Small/Mid Cap Value Portfolio
                 o    AB Value Portfolio
                 o    AB Balanced Wealth Strategy Portfolio
                 o    AB Dynamic Asset Allocation Portfolio
                 o    AB Global Bond Portfolio
                 o    AB Global Risk Allocation--Moderate Portfolio
                 o    AB Multi-Manager Alternative Strategies Portfolio
                          (the "Portfolios")
                 File Nos. 33-18647 and 811-05398
                -------------------------------------------------------


Dear Sir or Madam:

      On behalf of the above-referenced Portfolios of the AB Variable Products
Series Fund, Inc. (the "Fund"), we are transmitting a certification pursuant to
Rule 497(j) under the Securities Act of 1933. In this regard, we certify that
the Prospectuses and Statement of Additional Information for the Portfolios of
the Fund that would have been filed pursuant to Rule 497(c) do not differ from
those included in the most recent post-effective amendment to the Fund's
registration statement. That post-effective amendment was filed electronically
with the Securities and Exchange Commission on April 30, 2015.

                                                 Sincerely,


                                                 /s/  Anna C. Leist
                                                 ------------------
                                                      Anna C. Leist




cc: Stephen J. Laffey, AllianceBernstein Investments, Inc.
    Kathleen K. Clarke, Seward & Kissel LLP