SEWARD & KISSEL LLP

901 K Street, N.W.

Suite 800

Washington, D.C. 20001

Telephone: (202) 737-8833

Facsimile: (202) 737-5184

www.sewkis.com

 February 11, 2015

VIA EDGAR

Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Re:  AllianceBernstein Variable Products Series Fund, Inc.

· AB Global Bond Portfolio

· AB Global Risk Allocation – Moderate Portfolio

· AB Multi-Manager Alternative Strategies Portfolio

File Nos. 33-18647 and 811-05398

Dear Sir or Madam:

Pursuant to Rule 485(a) under the Securities Act of 1933, we are filing Post-Effective Amendment No. 62 under the Securities Act of 1933 (the "1933 Act") and Amendment No. 63 under the Investment Company Act of 1940 to the Registration Statement on Form N-1A of AllianceBernstein Variable Products Series Fund, Inc. (the Amendment").  We are making this filing for the purpose of registering three (3) new portfolios, the AB Global Bond Portfolio; the  AB Global Risk Allocation – Moderate Portfolio; and the AB Multi-Manager Alternative Strategies Portfolio.

Please direct any comments or questions to Kathleen K. Clarke or the undersigned at (202)737-8833.

Sincerely,

/s/ Anna C. Leist

    Anna C. Leist

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