SEWARD & KISSEL LLP
                              1200 G Street, N.W.
                                   Suite 350
                             Washington D.C. 20005

                           Telephone: (202) 737-8833
                           Facsimile: (202) 737-5184



                                                   May 6, 2011

VIA EDGAR
---------

Securities and Exchange Commission
100 F Street, N.E.
Washington, D.C.  20549


            AllianceBernstein Variable Products Series Fund, Inc.
               o   AllianceBernstein Money Market Portfolio
               o   AllianceBernstein Intermediate Bond Portfolio
               o   AllianceBernstein Large Cap Growth Portfolio
               o   AllianceBernstein Growth and Income Portfolio
               o   AllianceBernstein Growth Portfolio
               o   AllianceBernstein International Growth Portfolio
               o   AllianceBernstein Global Thematic Growth Portfolio
               o   AllianceBernstein Small Cap Growth Portfolio
               o   AllianceBernstein Real Estate Investment Portfolio
               o   AllianceBernstein International Value Portfolio
               o   AllianceBernstein Small/Mid Cap Value Portfolio
               o   AllianceBernstein Value Portfolio
               o   AllianceBernstein Balanced Wealth Strategy Portfolio
                     (the "Portfolios")
            File Nos. 33-18647 and 811-05398
            ------------------------------------------------------------

Dear Sir or Madam:

      On behalf of the above-referenced Portfolios of the AllianceBernstein
Variable Products Series Fund, Inc. (the "Fund"), we are transmitting a
certification pursuant to Rule 497(j) under the Securities Act of 1933. In this
regard, we certify that the Prospectuses for the Portfolios of the Fund that
would have been filed pursuant to Rule 497(c) do not differ from those included
in the most recent post-effective amendment to the Fund's registration
statement. That post-effective amendment was filed electronically with the
Securities and Exchange Commission on April 28, 2011.

      A copy of the Statement of Additional Information for the Portfolios of
the Fund will be filed under Rule 497(c) today.

                                                   Sincerely,


                                                   /s/  Young Seo
                                                   ---------------------------
                                                        Young Seo



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