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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Cash flows from operating activities:      
Net loss $ (22,085,702) $ (12,790,814) $ (9,377,533)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 75,114 36,193 47,656
Accrued Interest on CIRM award 1,311,836 133,905 0
(Gain) loss on disposal of assets 0 0 (4)
Change in fair value of warrant liability (3,812,398) (2,925,258) (529,774)
Financing expense 498,520 88,939 62,683
Stock-based compensation 1,228,987 916,028 654,260
Changes in assets and liabilities:      
Other assets 5,940 422,448 (9,097)
Supplies for clinical trials (221,545) (2,209,192) (227,097)
Deposits 2,220,766 (3,657,913) (339,259)
Accounts payable 125,363 805,320 (644,587)
Accrued liabilities 788,677 140,943 425,950
Net cash used in operating activities (19,864,442) (19,039,401) (9,936,802)
Cash flows from investing activities:      
Purchase of property and equipment (4,015) (169,750) (28,975)
Proceeds from sale of property and equipment 0 0 400
Net cash used in investing activities (4,015) (169,750) (28,575)
Cash flows from financing activities:      
Proceeds from exercise of stock options 0 6,750 1,045,000
Proceeds from exercise of warrants 208,750 0 0
Deferred financing costs (44,711) (15,041) 0
Proceeds from CIRM award 1,500,000 4,000,000 0
Proceeds from issuance of common stock and warrants, net of offering costs 6,345,868 14,599,627 0
Proceeds from issuance of common stock through controlled equity offering 691,187 0 4,496,322
Net cash provided by financing activities 8,701,094 18,591,336 5,541,322
Decrease in cash and cash equivalents (11,167,363) (617,815) (4,424,055)
Cash and cash equivalents, beginning of period 22,604,481 23,222,296 27,646,351
Cash and cash equivalents, end of period 11,437,118 22,604,481 23,222,296
Supplemental cash flows disclosures:      
Interest expense paid 0 0 0
Income taxes paid 0 0 0
Supplemental non-cash financing disclosures:      
Deferred offering costs included in accounts payable $ 55,505 $ 0 $ 0