Summary of Significant Accounting Policies and Going Concern - Additional Information (Details)		12 Months Ended
	Nov. 18, 2016 shares	Dec. 31, 2016 USD ($) $ / shares shares	Dec. 31, 2015 USD ($) $ / shares shares	Dec. 31, 2014 USD ($) $ / shares shares	Mar. 11, 2016 shares	Nov. 16, 2015 shares	Dec. 31, 2013 USD ($)
Accounting Policies [Abstract]
Accumulated deficit		$ 96,223,442	$ 74,137,740
Cash		11,437,118	22,604,481	$ 23,222,296			$ 27,646,351
Certificates of deposit		$ 3,462,617	$ 21,818,229
Property, Plant and Equipment [Line Items]
Weighted-average grant-date fair value of options granted (in usd per share) | $ / shares		$ 8.00	$ 13.60	$ 38.40
Shares authorized but unissued common stock (in shares) | shares		19,462,422
Common stock reserved (in shares) | shares		199,197			250,000
Tax benefit attributed to the stock-based compensation expense		$ 0
Unrecognized tax benefits, liability, penalties or interest accrued		$ 0	$ 0
Fair value of the intellectual property				$ 11,000,000
Reverse stock split ratio	0.025
Common stock, shares authorized (in shares) | shares	25,000,000	25,000,000	25,000,000	149,000,000		249,000,000
Common stock, par value (in usd per share) | $ / shares		$ 0.0001	$ 0.0001
Reclassified from common stock to APIC		$ 8,805
Shares excluded from the computation of diluted net loss per share (in shares) | shares		1,871,222	485,524	652,725
Computer Equipment
Property, Plant and Equipment [Line Items]
Estimated useful lives of property and equipment		3 years
Minimum
Property, Plant and Equipment [Line Items]
Estimated useful lives of property and equipment		3 years
Maximum
Property, Plant and Equipment [Line Items]
Estimated useful lives of property and equipment		5 years