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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Cash flows from operating activities:      
Net loss $ (12,790,814) $ (9,377,533) $ (8,800,563)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 36,193 47,656 50,402
Accrued Interest on CIRM award 133,905 0 0
(Gain) loss on disposal of assets 0 (4) 3,817
Change in fair value of warrant liability (2,925,258) (529,774) (642,411)
Financing expense 88,939 62,683 0
Stock-based compensation 916,028 654,260 724,212
Changes in assets and liabilities:      
Other assets 422,448 (9,097) (426,640)
Supplies for clinical trials (2,209,192) (227,097) 0
Deposits (3,657,913) (339,259) 0
Accounts payable 805,320 (644,587) 128,175
Accrued liabilities 140,943 425,950 175,791
Net cash used in operating activities (19,039,401) (9,936,802) (8,787,217)
Cash flows from investing activities:      
Purchase of property and equipment (169,750) (28,975) (44,372)
Proceeds from sale of property and equipment 0 400 0
Net cash used in investing activities (169,750) (28,575) (44,372)
Cash flows from financing activities:      
Proceeds from exercise of stock options 6,750 1,045,000 324,517
Proceeds from exercise of warrants 0 0 5,030,677
Deferred financing costs (15,041) 0 0
Proceeds from CIRM award 4,000,000 0 0
Proceeds from issuance of common stock and warrants net of offering costs 14,599,627 4,496,322 4,906,078
Net cash provided by financing activities 18,591,336 5,541,322 10,261,272
Increase (decrease) in cash and cash equivalents (617,815) (4,424,055) 1,429,683
Cash and cash equivalents, beginning of period 23,222,296 27,646,351 26,216,668
Cash and cash equivalents, end of period 22,604,481 23,222,296 27,646,351
Supplemental cash flows disclosures:      
Interest expense paid 0 0 0
Income taxes paid 0 0 0
Supplemental non-cash financing disclosures:      
Warrant liability converted to additional paid-in capital 0 0 1,145,659
Common stock issued for license rights 0 0 75,000
Deferred offering costs $ 33,936 $ 105,563 $ 0