Consolidated Statements of Shareholders' Equity - USD ($)	Total	Common stock issued for licensing rights	Common Stock	Common Stock Common stock issued for licensing rights	Additional Paid-in Capital	Additional Paid-in Capital Common stock issued for licensing rights	Accumulated Deficit
Beginning Balance at Dec. 31, 2012	$ 23,068,014		$ 5,150		$ 66,231,694		$ (43,168,830)
Beginning balance (in shares) at Dec. 31, 2012			51,500,996
Exercise of warrants	6,176,336		$ 344		6,175,992
Exercise of warrants (in shares)			3,441,551
Cashless exercise of warrants			$ 3		(3)
Cashless exercise of warrants (in shares)			31,155
Exercise of stock options	$ 324,517		$ 53		324,464
Exercise of stock options (in shares)	829,702		528,702
Cashless exercise of stock options			$ 15		(15)
Cashless exercise of stock options (in shares)			149,385
Stock based compensation	$ 724,215		$ 3		724,212
Common stock issued for license rights		$ 75,014		$ 17		$ 74,997
Common stock issued for license rights (in shares)				28,300
Common stock issued through controlled equity offering	4,906,061		$ 169		4,905,892
Common stock issued through controlled equity offering (in shares)			1,862,142
Net loss	(8,800,563)						(8,800,563)
Ending Balance at Dec. 31, 2013	26,473,594		$ 5,754		$ 78,437,233		(51,969,393)
Ending balance (in shares) at Dec. 31, 2013			57,542,231
Exercise of warrants	0		$ 0
Exercise of warrants (in shares)			0
Cashless exercise of warrants			$ 0
Cashless exercise of warrants (in shares)			0
Exercise of stock options	$ 1,045,000		$ 95		$ 1,044,905
Exercise of stock options (in shares)	624,047		950,000
Cashless exercise of stock options			$ 3		(3)
Cashless exercise of stock options (in shares)			28,473
Stock based compensation	$ 654,260				654,260
Common stock issued through controlled equity offering	4,496,322		$ 508		4,495,814
Common stock issued through controlled equity offering (in shares)			5,084,119
Net loss	(9,377,533)						(9,377,533)
Ending Balance at Dec. 31, 2014	23,291,643		$ 6,360		84,632,209		(61,346,926)
Ending balance (in shares) at Dec. 31, 2014			63,604,823
Exercise of stock options	$ 6,750		$ 3		6,747
Exercise of stock options (in shares)	50,000		25,000
Cashless exercise of stock options			$ 1		(1)
Cashless exercise of stock options (in shares)			10,326
Stock based compensation	$ 916,028		$ 2		916,026
Stock based compensation (in shares)			20,000
Common stock issued through controlled equity offering	10,296,689		$ 2,665		10,294,024
Common stock issued through controlled equity offering (in shares)			26,650,000
Net loss	(12,790,814)						(12,790,814)
Ending Balance at Dec. 31, 2015	$ 21,720,296		$ 9,031		$ 95,849,005		$ (74,137,740)
Ending balance (in shares) at Dec. 31, 2015			90,310,149