X0306 4 2022-02-03 0 0000822370 Emmaus Life Sciences, Inc. EMMA 0001517691 Niihara Yutaka 21250 HAWTHORNE BLVD. SUITE 800 TORRANCE CA 90503 1 1 1 0 Chairman and CEO Common stock, $0.001 par value 2022-02-03 4 P 0 6250 1.40 A 11148406 D Common stock, $0.001 par value 2022-02-04 4 P 0 7000 1.43 A 11155406 D Common stock, $0.001 par value 92794 I By Hope International Hospice, Inc. Common stock, $0.001 par value 63000 I By Soomi Niihara The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.36 to $1.44, inclusive. The reporting person undertakes to provide to Emmaus Life Sciences, Inc., any security holder of Emmaus Life Sciences, Inc., and the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote (1) and in footnote (3) to this Form 4. The shares shown include shares owned jointly with Soomi Niihara, the reporting person's wife. The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.32 to $1.50, inclusive. Hope International Hospice, Inc, is a California corporation of which Dr. Niihara and his wife are the sole shareholders and directors. Yutaka Niihara, M.D., M.P.H. 2022-02-07