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Stock-Based Compensation - Additional Information (Detail) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Feb. 07, 2018
Jan. 08, 2018
Jun. 30, 2018
Mar. 31, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Stock-based compensation expense     $ 503,000   $ 504,000 $ 1,069,000 $ 845,000  
Stock option exercised           230,626 0  
Cash received from option exercised           $ 1,400,000    
Employee service share-based compensation, nonvested awards, total compensation cost not yet recognized     $ 3,600,000     $ 3,600,000    
Employee service share-based compensation, nonvested awards, total compensation cost not yet recognized, period for recognition           2 years 6 months 29 days    
Merck KGaA, Darmstandt [Member] | Germany [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Term of supply agreement extended   4 years 6 months            
Time-Based Restricted Stock Units [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Weighted-average grant date fair values of options granted           $ 8.18 $ 5.11  
Shares, vested           9,300 0  
Performance-Based Restricted Stock Units [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Non-options stock expired               109,550
Non-options stock outstanding     48,650     48,650   76,450
Performance-Based Restricted Stock Units [Member] | Juniper Pharma Services [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Stock-based compensation expense     $ 36,000          
Non-options stock outstanding     20,850     20,850    
Employees [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Stock options granted           293,500 680,400  
Share-based compensation arrangement by share-based payment award, award vesting period           4 years    
Weighted-average grant date fair values of options granted           $ 3.40 $ 2.43  
Employees [Member] | Time-Based Restricted Stock Units [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Non-options stock granted           122,300 52,700  
Employees [Member] | Performance-Based Restricted Stock Units [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Non-options stock granted           0 186,000  
Non-Employees [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Stock options granted           0 0  
Stock-based compensation expense     $ 0     $ 0    
Reduction of stock-based compensation expense         $ 100,000   $ 100,000  
Non-Employee Directors [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Share-based compensation arrangement by share-based payment award, award vesting period           3 years    
Non-Employee Directors [Member] | Time-Based Restricted Stock Units [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Non-options stock granted           5,625 51,234  
Board of Director [Member] | Performance-Based Restricted Stock Units [Member]                
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Stock-based compensation expense       $ 100,000        
Shares, vested 27,800