X0202 3/A 2006-03-13 2006-03-17 0 0000821995 COLUMBIA LABORATORIES INC CBRX 0000808722 KNOTT DAVID M 485 UNDERHILL BLVD STE 205 SYOSSET NY 11791-3419 0 0 1 0 Common Stock, $.01 par value per share 995780 I By Knott Partners, L.P. Common Stock, $.01 par value per share 747200 I By Shoshone Partners, L.P. Common Stock, $.01 par value per share 600 I By Wife Common Stock, $.01 par value per share 1754270 I By Knott Partners Offshore Master Fund, L.P. Common Stock, $.01 par value per share 216600 I By Managed Accounts Common Stock, $.01 par value per share 3920 D Warrant to purchase Common Stock, $.01 par value per share 5.39 2006-09-13 2011-09-13 Common Stock, $.01 par value per share 75120 I By Knott Partners, L.P. Warrant to purchase Common Stock, $.01 par value per share 5.39 2006-09-13 2011-09-13 Common Stock, $.01 par value per share 80750 I By Shoshone Partners, L.P. Warrant to purchase Common Stock, $.01 par value per share 5.39 2006-09-13 2011-09-13 Common Stock, $.01 par value per share 202212 I By Knott Partners Offshore Master Fund, L.P. Warrant to purchase Common Stock, $.01 par value per share 5.39 2006-09-13 2011-09-13 Common Stock, $.01 par value per share 13175 I By Managed Accounts Series C Preferred Stock 3.50 Common Stock, $.01 par value per share 339428 I By Knott Partners, L.P. Series C Preferred Stock 3.50 Common Stock, $.01 par value per share 32000 D Series E Preferred Stock 2.00 Common Stock, $.01 par value per share 63000 I By Managed Accounts Series E Preferred Stock 2.00 Common Stock, $.01 par value per share 399000 I By Knott Partners, L.P. Series E Preferred Stock 2.00 Common Stock, $.01 par value per share 479000 I By Knott Partners Offshore Master Fund L.P. Series E Preferred Stock 2.00 Common Stock, $.01 par value per share 259000 I By Shoshone Partners, L.P. The Reporting Person is the managing member of Knott Partners Management, LLC, which is (i) the sole general partner of Shoshone Partners, L.P. and Knott Partners Offshore Master Fund LP., and (ii) the managing general partner of Knott Partners, L.P. This entry represents securities of the issuer held by institutional managed accounts for which Dorset Management Corporation provides investment management services (the "Managed Accounts"). As a result of the Reporting Person's interests in Knott Partners Management, LLC and in Dorset Management Corporation, the Reporting Person has investment discretion and control of the securities in this entry. The Reporting Person may be deemed to beneficially own an indirect pecuniary interest in securities in this entry as a result of a performance related fee. Except with respect to Knott Partners, L.P. and Shoshone Partners, L.P., in which the Reporting Person owns a beneficial interest, the Reporting Person disclaims beneficial ownership therein except to the extent ultimately realized. Each of Knott Partners, L.P. , Shoshone Partners, L.P., Knott Partners Offshore Master Fund, L.P. and the Managed Accounts disclaims beneficial ownership of securities reported as owned by any other party. These shares are currently convertible. These shares do not expire. This amendment filing is being made to reflect the transfer by Matterhorn Offshore Fund Limited to Knott Partners Offshore Master Fund, L.P. of record ownership of the securities reported in this entry. This amendment does not reflect any change of any pecuniary interest in these securities. /s/David M. Knott 2007-01-23