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<div style="margin-top:0pt; margin-bottom:0pt; " align="center"><b>NUVEEN LARGE CAP SELECT FUND </b></div> <p style="margin-top:12pt; margin-bottom:0pt; " align="center"><b>SUPPLEMENT DATED MAY 29, 2020 </b></p> <p style="margin-top:12pt; margin-bottom:0pt; " align="center"><b>TO THE PROSPECTUS DATED FEBRUARY 28, 2020 </b></p> <p style="margin-top:0pt;margin-bottom:0pt"> </p> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="4%" valign="top" align="left">1.</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="left">The section “Fund Summaries—Nuveen Large Cap Select Fund—Fees and Expenses of the Fund—Annual Fund Operating Expenses” is deleted in its entirety and replaced with the following: </div></td></tr></table> <p style="margin-top:8pt; margin-bottom:0pt; margin-left:2%; "><b>Annual Fund Operating Expenses </b></p> <p style="margin-top:0pt; margin-bottom:0pt; margin-left:2%; ">(expenses that you pay each year as a percentage of the value of your investment) </p> <p style="margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="97%" border="0" style="border-collapse:collapse; " align="center"> <tr> <td width="73%"></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="bottom" style="border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class A</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class C</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class I</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td></tr> <tr style=""> <td height="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Management Fees</div></td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.70% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.70% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.70% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td></tr> <tr style=""> <td height="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Distribution and/or Service (12b-1) Fees</div></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.25% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.00% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.00% </td> <td valign="bottom"> </td></tr> <tr style=""> <td height="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Other Expenses</div></td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right"> </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" ></td> <td valign="bottom" ></td> <td valign="bottom" ></td> <td valign="bottom" > </td> <td valign="bottom" ></td> <td valign="bottom" ></td> <td valign="bottom" ></td></tr> <tr style="font-size:1px "> <td height="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:2.40em; text-indent:-1.00em; ">Interest and Related Expenses<sup>3</sup></div></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.01% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.01% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.01% </td> <td valign="bottom"> </td></tr> <tr style=""> <td height="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:2.40em; text-indent:-1.00em; ">Remainder of Other Expenses</div></td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.24% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.24% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.24% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td></tr> <tr style="font-size:1px "> <td height="4" style="border-top:1px solid #000000"> </td> <td height="4" colspan="4" style="border-top:1px solid #000000"> </td> <td height="4" colspan="4" style="border-top:1px solid #000000"> </td> <td height="4" colspan="4" style="border-top:1px solid #000000"> </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Total Annual Fund Operating Expenses</div></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.20% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.95% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.95% </td> <td valign="bottom"> </td></tr> <tr style=""> <td height="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Fee Waivers and/or Expense Reimbursements<sup>4,5</sup></div></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">(0.14)%</td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">(0.14)%</td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">(0.14)%</td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td></tr> <tr style=""> <td height="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;border-bottom:1px solid #000000">Total Annual Fund Operating Expenses After Fee Waivers and/or Expense Reimbursements</td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">1.06% </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">1.81% </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">0.81% </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td></tr> </table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">1</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">The contingent deferred sales charge on Class C shares applies only to redemptions within 12 months of purchase. </div></td></tr></table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">2</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">Fee applies to the following types of accounts under $1,000 held directly with the Fund: individual retirement accounts (IRAs), Coverdell Education Savings Accounts and accounts established pursuant to the Uniform Transfers to Minors Act (UTMA) or Uniform Gifts to Minors Act (UGMA). </div></td></tr></table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">3</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">Includes interest expense and fees related to Fund borrowing arrangements. </div></td></tr></table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">4</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">Fee Waivers and/or Expense Reimbursements have been restated to reflect current fees. </div></td></tr></table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">5</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">The Fund’s investment adviser has agreed to waive fees and/or reimburse expenses through July 31, 2022 so that the total annual operating expenses of the Fund (excluding 12b-1 distribution and/or service fees, interest expenses, taxes, acquired fund fees and expenses, fees incurred in acquiring and disposing of portfolio securities and extraordinary expenses) do not exceed 0.80% of the average daily net assets of any class of Fund shares. This expense limitation may be terminated or modified prior to that date only with the approval of the Board of Directors of the Fund. </div></td></tr></table> <p style="margin-top:0pt;margin-bottom:0pt"> </p> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="4%" valign="top" align="left">2.</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="left">The section “Fund Summaries—Nuveen Large Cap Select Fund—Fees and Expenses of the Fund—Example” is deleted in its entirety and replaced with the following: </div></td></tr></table> <p style="margin-top:14pt; margin-bottom:0pt; margin-left:4%; "><b>Example </b></p> <p style="margin-top:10pt; margin-bottom:0pt; margin-left:4%; ">The following example is intended to help you compare the cost of investing in the Fund with the cost of investing in other mutual funds. The example assumes that you invest $10,000 in the Fund for the time periods indicated and then either redeem or do not redeem your shares at the end of a period. The example also assumes that your investment has a 5% return each year, that the Fund’s operating expenses remain the same and that the fee waivers currently in place are not renewed beyond July 31, 2022. Although your actual costs may be higher or lower, based on these assumptions your costs would be: </p> <p style="margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="92%" border="0" style="border-collapse:collapse; " align="center"> <tr> <td width="76%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="bottom" style="border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class A</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class C</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class I</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">1 Year</div></td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">677</td> <td valign="bottom" > </td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">184</td> <td valign="bottom" > </td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">83</td> <td valign="bottom" > </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">3 Years</div></td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">905</td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">582</td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">272</td> <td valign="bottom"> </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">5 Years</div></td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">1,168</td> <td valign="bottom" > </td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">1,023</td> <td valign="bottom" > </td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">495</td> <td valign="bottom" > </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="border-bottom:1px solid #000000"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">10 Years</div></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="border-bottom:1px solid #000000">$</td> <td valign="bottom" style="border-bottom:1px solid #000000" align="right">1,920</td> <td valign="bottom" style="border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="border-bottom:1px solid #000000">$</td> <td valign="bottom" style="border-bottom:1px solid #000000" align="right">2,249</td> <td valign="bottom" style="border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="border-bottom:1px solid #000000">$</td> <td valign="bottom" style="border-bottom:1px solid #000000" align="right">1,138</td> <td valign="bottom" style="border-bottom:1px solid #000000"> </td></tr> </table>
<div style="margin-top:0pt; margin-bottom:0pt; " align="center"><b>NUVEEN LARGE CAP SELECT FUND </b></div> <p style="margin-top:12pt; margin-bottom:0pt; " align="center"><b>SUPPLEMENT DATED MAY 29, 2020 </b></p> <p style="margin-top:12pt; margin-bottom:0pt; " align="center"><b>TO THE PROSPECTUS DATED FEBRUARY 28, 2020 </b></p> <p style="margin-top:0pt;margin-bottom:0pt"> </p> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="4%" valign="top" align="left">1.</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="left">The section “Fund Summaries—Nuveen Large Cap Select Fund—Fees and Expenses of the Fund—Annual Fund Operating Expenses” is deleted in its entirety and replaced with the following: </div></td></tr></table> <p style="margin-top:8pt; margin-bottom:0pt; margin-left:2%; "><b>Annual Fund Operating Expenses </b></p> <p style="margin-top:0pt; margin-bottom:0pt; margin-left:2%; ">(expenses that you pay each year as a percentage of the value of your investment) </p> <p style="margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="97%" border="0" style="border-collapse:collapse; " align="center"> <tr> <td width="73%"></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="2%"></td> <td></td> <td></td> <td></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="bottom" style="border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class A</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class C</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class I</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td></tr> <tr style=""> <td height="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Management Fees</div></td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.70% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.70% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.70% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td></tr> <tr style=""> <td height="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Distribution and/or Service (12b-1) Fees</div></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.25% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.00% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.00% </td> <td valign="bottom"> </td></tr> <tr style=""> <td height="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Other Expenses</div></td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right"> </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" ></td> <td valign="bottom" ></td> <td valign="bottom" ></td> <td valign="bottom" > </td> <td valign="bottom" ></td> <td valign="bottom" ></td> <td valign="bottom" ></td></tr> <tr style="font-size:1px "> <td height="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:2.40em; text-indent:-1.00em; ">Interest and Related Expenses<sup>3</sup></div></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.01% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.01% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.01% </td> <td valign="bottom"> </td></tr> <tr style=""> <td height="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:2.40em; text-indent:-1.00em; ">Remainder of Other Expenses</div></td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.24% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.24% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" > </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td> <td valign="bottom" style="padding-bottom:3pt ;" align="right">0.24% </td> <td valign="bottom" style="padding-bottom:3pt ;" > </td></tr> <tr style="font-size:1px "> <td height="4" style="border-top:1px solid #000000"> </td> <td height="4" colspan="4" style="border-top:1px solid #000000"> </td> <td height="4" colspan="4" style="border-top:1px solid #000000"> </td> <td height="4" colspan="4" style="border-top:1px solid #000000"> </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Total Annual Fund Operating Expenses</div></td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.20% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">1.95% </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom" align="right">0.95% </td> <td valign="bottom"> </td></tr> <tr style=""> <td height="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td> <td height="4" colspan="4" ></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">Fee Waivers and/or Expense Reimbursements<sup>4,5</sup></div></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">(0.14)%</td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">(0.14)%</td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">(0.14)%</td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" > </td></tr> <tr style=""> <td height="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td> <td height="4" colspan="4"></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="padding-bottom:3pt ;border-bottom:1px solid #000000">Total Annual Fund Operating Expenses After Fee Waivers and/or Expense Reimbursements</td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">1.06% </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">1.81% </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000" align="right">0.81% </td> <td valign="bottom" style="padding-bottom:3pt ;border-bottom:1px solid #000000"> </td></tr> </table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">1</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">The contingent deferred sales charge on Class C shares applies only to redemptions within 12 months of purchase. </div></td></tr></table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">2</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">Fee applies to the following types of accounts under $1,000 held directly with the Fund: individual retirement accounts (IRAs), Coverdell Education Savings Accounts and accounts established pursuant to the Uniform Transfers to Minors Act (UTMA) or Uniform Gifts to Minors Act (UGMA). </div></td></tr></table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">3</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">Includes interest expense and fees related to Fund borrowing arrangements. </div></td></tr></table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">4</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">Fee Waivers and/or Expense Reimbursements have been restated to reflect current fees. </div></td></tr></table> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="3%"> </td> <td width="2%" valign="top" align="left">5</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="justify">The Fund’s investment adviser has agreed to waive fees and/or reimburse expenses through July 31, 2022 so that the total annual operating expenses of the Fund (excluding 12b-1 distribution and/or service fees, interest expenses, taxes, acquired fund fees and expenses, fees incurred in acquiring and disposing of portfolio securities and extraordinary expenses) do not exceed 0.80% of the average daily net assets of any class of Fund shares. This expense limitation may be terminated or modified prior to that date only with the approval of the Board of Directors of the Fund. </div></td></tr></table> <p style="margin-top:0pt;margin-bottom:0pt"> </p> <table style="border-collapse:collapse; " border="0" cellpadding="0" cellspacing="0" width="100%"> <tr style="page-break-inside:avoid"> <td width="4%" valign="top" align="left">2.</td> <td align="left" valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; " align="left">The section “Fund Summaries—Nuveen Large Cap Select Fund—Fees and Expenses of the Fund—Example” is deleted in its entirety and replaced with the following: </div></td></tr></table> <p style="margin-top:14pt; margin-bottom:0pt; margin-left:4%; "><b>Example </b></p> <p style="margin-top:10pt; margin-bottom:0pt; margin-left:4%; ">The following example is intended to help you compare the cost of investing in the Fund with the cost of investing in other mutual funds. The example assumes that you invest $10,000 in the Fund for the time periods indicated and then either redeem or do not redeem your shares at the end of a period. The example also assumes that your investment has a 5% return each year, that the Fund’s operating expenses remain the same and that the fee waivers currently in place are not renewed beyond July 31, 2022. Although your actual costs may be higher or lower, based on these assumptions your costs would be: </p> <p style="margin-top:0pt;margin-bottom:0pt"> </p> <table cellspacing="0" cellpadding="0" width="92%" border="0" style="border-collapse:collapse; " align="center"> <tr> <td width="76%"></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="3%"></td> <td></td> <td></td> <td></td></tr> <tr style="page-break-inside:avoid ; "> <td valign="bottom" style="border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class A</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class C</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" colspan="2" align="right" style="border-bottom:1px solid #000000"><b>Class I</b></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">1 Year</div></td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">677</td> <td valign="bottom" > </td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">184</td> <td valign="bottom" > </td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">83</td> <td valign="bottom" > </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">3 Years</div></td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">905</td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">582</td> <td valign="bottom"> </td> <td valign="bottom"> </td> <td valign="bottom">$</td> <td valign="bottom" align="right">272</td> <td valign="bottom"> </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" > <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">5 Years</div></td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">1,168</td> <td valign="bottom" > </td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">1,023</td> <td valign="bottom" > </td> <td valign="bottom" > </td> <td valign="bottom" >$</td> <td valign="bottom" align="right">495</td> <td valign="bottom" > </td></tr> <tr style="page-break-inside:avoid ; "> <td valign="top" style="border-bottom:1px solid #000000"> <div style=" margin-top:0pt ; margin-bottom:0pt; margin-left:1.00em; text-indent:-1.00em; ">10 Years</div></td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="border-bottom:1px solid #000000">$</td> <td valign="bottom" style="border-bottom:1px solid #000000" align="right">1,920</td> <td valign="bottom" style="border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="border-bottom:1px solid #000000">$</td> <td valign="bottom" style="border-bottom:1px solid #000000" align="right">2,249</td> <td valign="bottom" style="border-bottom:1px solid #000000"> </td> <td valign="bottom" style=" border-bottom:1px solid #000000"> </td> <td valign="bottom" style="border-bottom:1px solid #000000">$</td> <td valign="bottom" style="border-bottom:1px solid #000000" align="right">1,138</td> <td valign="bottom" style="border-bottom:1px solid #000000"> </td></tr> </table>
Annual Fund Operating Expenses (expenses that you pay each year as a percentage of the value of your investment)
Example
The following example is intended to help you compare the cost of investing in the Fund with the cost of investing in other mutual funds. The example assumes that you invest $10,000 in the Fund for the time periods indicated and then either redeem or do not redeem your shares at the end of a period. The example also assumes that your investment has a 5% return each year, that the Fund’s operating expenses remain the same and that the fee waivers currently in place are not renewed beyond July 31, 2022. Although your actual costs may be higher or lower, based on these assumptions your costs would be:
The contingent deferred sales charge on Class C shares applies only to redemptions within 12 months of purchase.
Fee Waivers and/or Expense Reimbursements have been restated to reflect current fees.
July 31, 2022
0.007
0.007
0.007
0.0025
0.01
0
0.0001
0.0001
0.0001
0.0024
0.0024
0.0024
0.012
0.0195
0.0095
-0.0014
-0.0014
-0.0014
0.0106
0.0181
0.0081
677
184
83
905
582
272
1168
1023
495
1920
2249
1138
677
184
83
905
582
272
1168
1023
495
1920
2249
1138
N-1A