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INVESTMENTS (Details Narrative) - USD ($)
12 Months Ended
Dec. 31, 2018
Oct. 08, 2018
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 18, 2018
Dec. 15, 2017
Restructuring Cost and Reserve [Line Items]              
Investments          
Investments, impairment     $ 500,000 $ 500,000      
Preprogen Agreement [Member]              
Restructuring Cost and Reserve [Line Items]              
Escrow cash received   $ 200,583         $ 400,000
Percentage of royalty from sale   5.00%          
Royalty payments received   $ 200,000          
Investments $ 222,000       $ 0    
Investments, impairment $ 278,000       $ 222,000    
Preprogen LLC [Member]              
Restructuring Cost and Reserve [Line Items]              
Axquired percentage           15.00%