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Stock-Based Compensation, Stock Option Activity (Details) - Stock Options - USD ($)
$ / shares in Units, $ in Millions
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Stock option activity    
Options outstanding at the beginning of the period (in shares) 65,300,748  
Non-vested options, options granted (in shares) 532,721  
Options exercised (in shares) (646,759)  
Options forfeited (in shares) (136,140)  
Options outstanding at the end of the period (in shares) 65,050,570 65,300,748
Vested and non-vested options expected to vest at the end of the period (in shares) 62,416,843  
Exercisable at the end of the period (in shares) 33,332,906  
Weighted Average Exercise Price    
Weighted average exercise price, options outstanding at the beginning of the period (in dollars per share) $ 42.00  
Weighted average exercise price, options granted (in dollars per share) 85.92  
Weighted average exercise price, options exercised (in dollars per share) 30.24  
Weighted average exercise price, options forfeited (in dollars per share) 47.07  
Weighted average exercise price, options outstanding at the end of the period (in dollars per share) 42.46 $ 42.00
Weighted average exercise price, vested and non-vested options expected to vest (in dollars per share) 42.14  
Weighted average exercise price, exercisable (in dollars per share) $ 35.41  
Weighted Average Remaining Contractual Term    
Weighted average remaining contractual term of options outstanding 6 years 3 months 7 days 6 years 5 months 19 days
Weighted average remaining contractual term of options vested options and non-vested expected to vest 6 years 2 months 12 days  
Weighted average remaining contractual term of options exercisable 4 years 11 months 23 days  
Aggregate Intrinsic Value    
Aggregate intrinsic value of options outstanding $ 2,145.0 $ 2,968.8
Aggregate intrinsic value of options, vested and non-vested options expected to vest 2,078.2  
Aggregate intrinsic value of options exercisable $ 1,331.2