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Balance Sheet Information
3 Months Ended
Mar. 31, 2012
Balance Sheet Information [Abstract]  
Balance Sheet Information
Balance Sheet Information

The following tables provide details of selected balance sheet line items as of March 31, 2012 and December 31, 2011 (in thousands):

Inventories
 
 
March 31,
2012
 
December 31,
2011
Raw materials and supplies
 
$
18,170

 
$
19,429

Work in process
 
28,192

 
27,464

Finished goods
 
34,969

 
30,993

Inventories
 
$
81,331

 
$
77,886







Property, Plant and Equipment, Net
 
 
March 31,
2012
 
December 31,
2011
Land
 
$
19,369

 
$
19,355

Building
 
79,809

 
80,005

Machinery and equipment
 
219,786

 
213,729

Building improvements
 
64,956

 
60,628

Furniture and fixtures
 
22,270

 
21,790

Construction in-progress
 
1,199

 
2,789

Property, plant and equipment, at cost
 
407,389

 
398,296

Less: accumulated depreciation and amortization
 
(227,119
)
 
(222,215
)
Property, plant and equipment, net
 
$
180,270

 
$
176,081



Purchased Intangibles
 
 
March 31, 2012
 
December 31, 2011

 
Gross
 
Accumulated Amortization
 
Gross
 
Accumulated Amortization
Customer relationships
 
$
77,720

 
$
(17,447
)
 
$
77,326

 
$
(15,723
)
Developed technology
 
59,206

 
(38,855
)
 
59,206

 
(38,292
)
Trademarks
 
10,879

 
(1,631
)
 
10,817

 
(1,487
)
Trade names
 
7,300

 
(526
)
 
7,300

 
(435
)
In-process research and development
 
7,907

 

 
7,907

 

Total purchased intangibles
 
$
163,012

 
$
(58,459
)
 
$
162,556

 
$
(55,937
)


License, Manufacturing Access Fees and Other Assets, Net
 
 
March 31,
2012
 
December 31,
2011
License and manufacturing access fees
 
$
68,488

 
$
67,906

Investment in Qualigen, Inc.
 
5,404

 
5,404

Investment in DiagnoCure, Inc.
 
5,000

 
5,000

Investment in Roka Bioscience, Inc.
 
4,705

 
4,705

Other assets
 
11,909

 
11,257

License, manufacturing access fees and other assets, at cost
 
95,506

 
94,272

Less: accumulated amortization
 
(34,260
)
 
(32,534
)
License, manufacturing access fees and other assets, net
 
$
61,246

 
$
61,738



Other Accrued Expenses
 
 
March 31,
2012
 
December 31,
2011
 
 
 
 
 
Research and development
 
$
5,431

 
$
3,554

Professional fees
 
3,471

 
1,148

Royalties
 
2,778

 
3,047

Marketing and sales
 
1,754

 
1,261

Other
 
4,150

 
3,836

Other accrued expenses
 
$
17,584

 
$
12,846